ID A0A2C6A328_9HYPO Unreviewed; 755 AA.
AC A0A2C6A328;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=CDD83_10800 {ECO:0000313|EMBL:PHH86061.1};
OS Cordyceps sp. RAO-2017.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=2004951 {ECO:0000313|EMBL:PHH86061.1, ECO:0000313|Proteomes:UP000221130};
RN [1] {ECO:0000313|Proteomes:UP000221130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1346 {ECO:0000313|Proteomes:UP000221130};
RA de Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PHH86061.1, ECO:0000313|Proteomes:UP000221130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1346 {ECO:0000313|EMBL:PHH86061.1,
RC ECO:0000313|Proteomes:UP000221130};
RA De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT behavioral manipulation genes and a possible major role for enterotoxins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC clathrin to receptors in coated vesicles. Clathrin-associated protein
CC complexes are believed to interact with the cytoplasmic tails of
CC membrane proteins, leading to their selection and concentration.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH86061.1}.
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DR EMBL; NJEV01000909; PHH86061.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C6A328; -.
DR STRING; 2004951.A0A2C6A328; -.
DR OrthoDB; 648032at2759; -.
DR Proteomes; UP000221130; Unassembled WGS sequence.
DR GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF3; AP COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000221130};
KW Transport {ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 15..531
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT REGION 645..755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 724..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 82071 MW; 750374840FCC8D42 CRC64;
MAVNRIRGAF AAPRKGETFE LRAGLVSQYA YERKESIQKT IMAMTLGKDV SALFPDVLKN
IATSDLDQKK LVYLYLMNYA KSHPDLCILA VNTFVQDSED PNPLVRALAI RTMGCIRVDK
MVDYMEEPLR KTLRDESPYV RKTAAICVAK LFDLNPSMCI ENGFLESLQE LIGDPNPMVV
ANSVQALAEI TETAPETRAL VVTAPTLKKL LMALNECTEW GRITILSTLA DYQSNDVKES
EHICERVVPQ FQHVNPSVVL AAIKAVFIHM RAVNPELVRS YLKKMAPPLV TLVASAPEVQ
YVALRNIDLL LQAKPDILSK ELRVFFCKYN DPPYVKMQKL EIMVRIANEK NYEQLLAELK
EYALEVDMDF VRRAVKAIGQ VAIKIENASG KCVQALEDLI STKVNYVVQE VVVVIKDILR
KYPGYEGVIP TLCKYIDELD EPDARGSLIW IVGEYAEKIN NADQILESFV EGFMEEFTQT
QLQILTAVVK LFLKKPDNTQ GLVQKVLQSA TAENDNPDIR DRAYVYWRLL SGDLDVAKNI
ILSRKPTIST TMTSLPTSLL EQLLAELSTL ASVYHKPPES FVGKGRFGAD EIQRAAILEQ
RQNAAENPIA ASVAAAAAGA NGSGAEGSQS NVENLLDIDF DGAAPASQEQ GSATATPDRV
ASPTGAAASG GMADMMSMFD APPPAATSSG GGGGGGGGES VGGGISDLMS GFEGLDFGGS
QPNQPLPAAM QLQNAAQKGG AQAPKKDSDD LLGLL
//
