ID A0A2C6A7L3_9HYPO Unreviewed; 1398 AA.
AC A0A2C6A7L3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Raptor N-terminal CASPase-like domain-containing protein {ECO:0000259|SMART:SM01302};
GN ORFNames=CDD83_7974 {ECO:0000313|EMBL:PHH88092.1};
OS Cordyceps sp. RAO-2017.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=2004951 {ECO:0000313|EMBL:PHH88092.1, ECO:0000313|Proteomes:UP000221130};
RN [1] {ECO:0000313|Proteomes:UP000221130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1346 {ECO:0000313|Proteomes:UP000221130};
RA de Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PHH88092.1, ECO:0000313|Proteomes:UP000221130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1346 {ECO:0000313|EMBL:PHH88092.1,
RC ECO:0000313|Proteomes:UP000221130};
RA De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT behavioral manipulation genes and a possible major role for enterotoxins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat RAPTOR family.
CC {ECO:0000256|ARBA:ARBA00009257}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH88092.1}.
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DR EMBL; NJEV01000498; PHH88092.1; -; Genomic_DNA.
DR STRING; 2004951.A0A2C6A7L3; -.
DR OrthoDB; 103066at2759; -.
DR Proteomes; UP000221130; Unassembled WGS sequence.
DR GO; GO:0031931; C:TORC1 complex; IEA:InterPro.
DR GO; GO:0031929; P:TOR signaling; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR004083; Raptor.
DR InterPro; IPR029347; Raptor_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR12848; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR PANTHER; PTHR12848:SF16; REGULATORY-ASSOCIATED PROTEIN OF MTOR; 1.
DR Pfam; PF14538; Raptor_N; 1.
DR PRINTS; PR01547; YEAST176DUF.
DR SMART; SM01302; Raptor_N; 1.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000221130};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 154..307
FT /note="Raptor N-terminal CASPase-like"
FT /evidence="ECO:0000259|SMART:SM01302"
FT REPEAT 1283..1305
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..925
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 940..985
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 951..965
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..984
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1398 AA; 158238 MW; FBAEDA2AB48F2E7F CRC64;
MTLRSDMHGS LPSNATTNGE TSRFRAQGDS SPDRDASDNS GDRRPSSAPG RENGAPAPAP
PAAGDVPAPD RPAKPQLHRS KSDYAARQAD DSDPDDDIRE WGARHGFEDH YQSEHIISQL
VNNWYMYFTD KRHETTGKPK PLDYDLQDWR QRDRLKTVSA ALAVCLNIGV EPPDQLKTTP
GAKLEAWTDP TIPPIQKALE NIGKALQAQY ETLAIRARYK QYLDPSVEET KKFCVSLRRN
AKDERVLLHY NGHGVPKPTA SGEIWVFNKT YTQYIPVSLY DLQHWLQAPT IFVWDCSEAG
NILNNYHRFV EKHEEEEDEA AERDPHYEKT NYRPYIHLAA CAIKENLPTN PLLPADLFTA
CLTTPIEMAL WFFVLQNPLK TNLTPERAKQ LPGRLQERRT PLGELNWIFT AITDSIAWTT
LPRDLFRKFF RQDLMVAALF RNFLLAQRVM TVYGCHPQSY PALPDTHQHP LWETWDLAVD
MALAQLPMLE RKESEGVEYE YQYQNSTFFT EQLTAFDVYL TRGDAMAQKP PDQLPVVLQV
LLSQQHRVRA LILLGRFLDL GPWSVQLALS IGIFPYVLKL LQSAAVELKP VMVFIWARLV
AVDISCQQDL IKDSGYSYFA QILKPSEGLP VVDGDEHKAM CAFILAMLCK DYKNGQMVCN
QTDIMSYCLA HLQNEHNPLL RQWACLCISQ LWQGLPEPKW RGIRENAYVK LAFLIRDPCC
EVRAAMIHAM TTFLGIPDLT DEVARIEESI AWTILEMGTD GSPMVRKELL VFLSHFITRF
ENKFLVAAYE QLQEEKDYLF FPPQDDGQDH KMGLHYARPE NRNKDGTIKI AAQGLSHNTV
YMACWKHALI LSVDPHPEVQ REATVIVDYV HNALINSSIG EPAHVLMRDI QWRAKKAAQR
QAASATHRNT LRGVPNTPPL PSPGLLRRTA SLLFQSFIGG EDKSSPLAPG GTRPPRSPST
KVPPDQMSAP PEQNDQSGSP ASYNVAREPL SGAFHERDLG KAPVLPLKSG FLDWSIEYFR
EPQMKASEAD EPGSTEYNER LWRRARNENL LRETQPLKQL AGSHKWNHQL GIVNNGAQPA
KMTFHQYEDH LAVSDDGNTV SVWDWKKQGR LSKFSNGNPE GSKISDIKFI NEDDQAFLLT
GSSDGVIRVY RNYDSDRTIE LATSWRALTH MVPSNVNSGM VFDWQQVTGR VLVAGDVRVI
RVWYAAHETC VMDIPARSGS CVTSLTSDQM TGNIFVAGFG DGAVRVFDTR KRPQDSMVRK
WKDESDRQWI KSVHMQRGGQ RELLSASRNG KVKVWDIRMD RPLHAIQTTR DTLRTMSTHE
HLPVFAVGTS QHAVKVFNLE GNELSRLEPY SSFLQQTRGG PISATAFHPH RPILGCSARG
DHHVNLFTCE KAEPMHFG
//
