ID   A0A2C6A930_9HYPO        Unreviewed;       274 AA.
AC   A0A2C6A930;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=HMA domain-containing protein {ECO:0000259|PROSITE:PS50846};
GN   ORFNames=CDD83_7380 {ECO:0000313|EMBL:PHH88550.1};
OS   Cordyceps sp. RAO-2017.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX   NCBI_TaxID=2004951 {ECO:0000313|EMBL:PHH88550.1, ECO:0000313|Proteomes:UP000221130};
RN   [1] {ECO:0000313|Proteomes:UP000221130}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1346 {ECO:0000313|Proteomes:UP000221130};
RA   de Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PHH88550.1, ECO:0000313|Proteomes:UP000221130}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1346 {ECO:0000313|EMBL:PHH88550.1,
RC   ECO:0000313|Proteomes:UP000221130};
RA   De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT   "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT   behavioral manipulation genes and a possible major role for enterotoxins.";
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHH88550.1}.
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DR   EMBL; NJEV01000429; PHH88550.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C6A930; -.
DR   STRING; 2004951.A0A2C6A930; -.
DR   OrthoDB; 5480493at2759; -.
DR   Proteomes; UP000221130; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00371; HMA; 1.
DR   Gene3D; 3.30.70.100; -; 1.
DR   InterPro; IPR006121; HMA_dom.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   PANTHER; PTHR46594; P-TYPE CATION-TRANSPORTING ATPASE; 1.
DR   PANTHER; PTHR46594:SF4; P-TYPE CATION-TRANSPORTING ATPASE; 1.
DR   Pfam; PF00403; HMA; 1.
DR   SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR   PROSITE; PS50846; HMA_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221130};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        184..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        212..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          33..100
FT                   /note="HMA"
FT                   /evidence="ECO:0000259|PROSITE:PS50846"
SQ   SEQUENCE   274 AA;  29288 MW;  D23C8D3415C387B7 CRC64;
     MPHASLTLKR VRADKANAVP SASDVENQAV GSEHVVLCVS GMTCTGCETK LNRTLATVHG
     VGSLKTSLVL SRAEFDVDLR LVAVADVIKH LERTTEFKCE RIADRGSSLD VLVAGDGTSF
     VDRPWPEGVM DMSLADKGVV RITFDPAIVG ARDLLTTHLG PDVRLAPVCA DASLKAGGKH
     VRHVGFVTML SSVLTVPVLV MAWAPLPKHE MAYSSASLAL ATIVQIFVAG PFYPKALKAL
     VFSRVIEMDL LIVLSTSAAY VFSTVSFSRR ARCS
//