ID A0A2C6A9K2_9HYPO Unreviewed; 513 AA.
AC A0A2C6A9K2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Pyridoxamine kinase/Phosphomethylpyrimidine kinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CDD83_7703 {ECO:0000313|EMBL:PHH88311.1};
OS Cordyceps sp. RAO-2017.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Cordycipitaceae; Cordyceps.
OX NCBI_TaxID=2004951 {ECO:0000313|EMBL:PHH88311.1, ECO:0000313|Proteomes:UP000221130};
RN [1] {ECO:0000313|Proteomes:UP000221130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1346 {ECO:0000313|Proteomes:UP000221130};
RA de Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PHH88311.1, ECO:0000313|Proteomes:UP000221130}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1346 {ECO:0000313|EMBL:PHH88311.1,
RC ECO:0000313|Proteomes:UP000221130};
RA De Bekker C., Evans H.C., Brachmann A., Hughes D.P.;
RT "Ant-infecting Ophiocordyceps genomes reveal a high diversity of potential
RT behavioral manipulation genes and a possible major role for enterotoxins.";
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHH88311.1}.
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DR EMBL; NJEV01000465; PHH88311.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C6A9K2; -.
DR STRING; 2004951.A0A2C6A9K2; -.
DR OrthoDB; 5477821at2759; -.
DR Proteomes; UP000221130; Unassembled WGS sequence.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0050334; F:thiaminase activity; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR CDD; cd19367; TenA_C_ScTHI20-like; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 1.20.910.10; Heme oxygenase-like; 1.
DR InterPro; IPR016084; Haem_Oase-like_multi-hlx.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR004305; Thiaminase-2/PQQC.
DR InterPro; IPR027574; Thiaminase_II.
DR NCBIfam; TIGR04306; salvage_TenA; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF03070; TENA_THI-4; 1.
DR SUPFAM; SSF48613; Heme oxygenase-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000221130}.
FT DOMAIN 13..281
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
FT DOMAIN 304..508
FT /note="Thiaminase-2/PQQC"
FT /evidence="ECO:0000259|Pfam:PF03070"
SQ SEQUENCE 513 AA; 55504 MW; ACA9E979802D127C CRC64;
MAPGRVLLVA GSDCSGGAGL EAGQKVLAAH GCYAMTATTA LTVQDTTGVK AIHVIPASFV
EQQIKACLED VGADVITTGM LAAADTIDAV ARQVSKHKDA VALVVDPVMV STSGTQLLPH
EAIRVLAQRI LPLTTILTPN IPEAELILSE MGEARDSTAS RSQPAIESVA DVEALGRHIQ
ALGPTWVLVK GGHVPLSADL TVAPTEAERQ AVVDVLVGPE GYVLRLQSPW QHSTSTHGTG
SAISAGLSST QDVPAAVRAA CRYVEAGIRS APGLGCGHGP LGHFHSNYHL PFSPGYFIEY
LLNHPDVTTV WERFVHHSFV MAIGDGTLPL QSFQGYIIQD YLYLIHFSRA NALAAYKAKN
AEEIKTANEI VGHIMRELDL HINYCKSFGI SVSEMQATEE QQACTAYTRY VLDVGQSDDW
LALQVALAPC LLGYGAVAQM LHEHPRTRRE GNAYWPWILN YVADDYVRAV RLGSQRIEDG
ARLQSPSRIQ ELVRIFVHAT KMEIGFWEIF PHK
//
