ID   A0A2C6CUI2_9BACT        Unreviewed;       669 AA.
AC   A0A2C6CUI2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=CEQ90_02115 {ECO:0000313|EMBL:PHI21628.1};
OS   Lewinellaceae bacterium SD302.
OC   Bacteria; Bacteroidota; Saprospiria; Saprospirales; Lewinellaceae.
OX   NCBI_TaxID=2014804 {ECO:0000313|EMBL:PHI21628.1, ECO:0000313|Proteomes:UP000223945};
RN   [1] {ECO:0000313|EMBL:PHI21628.1, ECO:0000313|Proteomes:UP000223945}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SD302 {ECO:0000313|EMBL:PHI21628.1,
RC   ECO:0000313|Proteomes:UP000223945};
RA   Wang K.;
RT   "The draft genome sequence of Lewinellaceae bacterium SD302.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHI21628.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PDLQ01000002; PHI21628.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C6CUI2; -.
DR   OrthoDB; 9805121at2; -.
DR   Proteomes; UP000223945; Unassembled WGS sequence.
DR   CDD; cd01465; vWA_subgroup; 1.
DR   Gene3D; 2.60.40.1120; Carboxypeptidase-like, regulatory domain; 1.
DR   Gene3D; 2.170.130.10; TonB-dependent receptor, plug domain; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR008969; CarboxyPept-like_regulatory.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR022156; Uncharacterised_YfbK_N.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   InterPro; IPR021908; YfbK_C.
DR   PANTHER; PTHR47322; SUSC HOMOLOG-RELATED; 1.
DR   PANTHER; PTHR47322:SF22; TONB-DEPENDENT RECEPTOR SUSC; 1.
DR   Pfam; PF13620; CarboxypepD_reg; 1.
DR   Pfam; PF00092; VWA; 1.
DR   Pfam; PF12450; vWF_A; 1.
DR   Pfam; PF12034; YfbK_C; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR   SUPFAM; SSF56935; Porins; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000223945};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..669
FT                   /note="VWFA domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012406246"
FT   DOMAIN          328..506
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          153..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   669 AA;  73079 MW;  BE4A9E92CCDDEB77 CRC64;
     MRYTYSFFLF LFLVASAAGQ TSLKGKVTDQ DSGNEGMPFA SVALKLGEKI IQGVNTDLDG
     NYLFKSLNPG VYNLEVSYTG YATQRLTGVL IKAGQVNVVN VTMSAGVSLD EVMVTGYKVP
     LIDQDNTTQG KTVSSEEIRN LPTRSINAIS ATTAGVGAAD SRRKKRRRKD RHNKEAIQPA
     AVPIRGNRSN SGNYYVDGIR VHGKLDTATP VDADNPEPRN DEQYNEITEN EFIATEKEAI
     STLSTDVDRA AYANVRGLIN AGQEVPKDAV RIEEMINYFR YSDPFPKGKD PVAIRTELTE
     CPWNKDNQLL RIGVRARGMA PQQAPASNVV FLVDVSGSMN SANKLPLVTK ALKMLASNLR
     QEDKVSIVVY AGAAGLVLPP TSGANTPQIT AVLDNLRARG STAGGAGIEL AYKTARENFI
     KGGNNRIILV TDGDFNVGTS DQESLVKLIE KERESGVFLT VIGCGRGNIQ DGTMQELADR
     GNGNHGYLDS YAEARKLLVD EFGGTVYTVA KDVKLQLEFD PERVAGYRLI GYENRLLATE
     DFDDDTKDAA EMGAGHVVTV LYEIEPAKKK RSQQNDLGEL RLRYKQPNDS ISKKMTWQVG
     GRVAGFSKAS EDLRWGAAVA EFGLLLRDSK FKGEANWEDL AKRTKAALGA DPFGYRKEML
     GLIELVKAR
//