ID A0A2C6KBG4_9APIC Unreviewed; 7699 AA.
AC A0A2C6KBG4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Hect-domain (Ubiquitin-transferase) domain-containing {ECO:0000313|EMBL:PHJ18170.1};
GN ORFNames=CSUI_008005 {ECO:0000313|EMBL:PHJ18170.1};
OS Cystoisospora suis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Cystoisospora.
OX NCBI_TaxID=483139 {ECO:0000313|EMBL:PHJ18170.1, ECO:0000313|Proteomes:UP000221165};
RN [1] {ECO:0000313|EMBL:PHJ18170.1, ECO:0000313|Proteomes:UP000221165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wien I {ECO:0000313|EMBL:PHJ18170.1,
RC ECO:0000313|Proteomes:UP000221165};
RX PubMed=28161402; DOI=10.1016/j.ijpara.2016.11.007;
RA Palmieri N., Shrestha A., Ruttkowski B., Beck T., Vogl C., Tomley F.,
RA Blake D.P., Joachim A.;
RT "The genome of the protozoan parasite Cystoisospora suis and a reverse
RT vaccinology approach to identify vaccine candidates.";
RL Int. J. Parasitol. 47:189-202(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHJ18170.1}.
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DR EMBL; MIGC01004360; PHJ18170.1; -; Genomic_DNA.
DR VEuPathDB; ToxoDB:CSUI_008005; -.
DR OrthoDB; 264772at2759; -.
DR Proteomes; UP000221165; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd14296; UBA1_scUBP14_like; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR InterPro; IPR025527; HUWE1/Rev1_UBM.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR34491; A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR34491:SF150; COILED-COIL DOMAIN-CONTAINING PROTEIN 62; 1.
DR Pfam; PF00627; UBA; 1.
DR Pfam; PF14377; UBM; 3.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000221165};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PHJ18170.1}.
FT DOMAIN 1258..1301
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 243..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 287..361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..636
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 692..739
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 820..971
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 988..1016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1211..1259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1303..1529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1568..1587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1600..1659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1685..1741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1819..1981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2111..2213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2321..2352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2419..2441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2478..2521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2536..2576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2595..2622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2641..2666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2773..2794
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2887..2948
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3062..3318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3331..3433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3448..3496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3534..3605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3624..3662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3788..3926
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4020..4041
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4070..4110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4232..4270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4303..4328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4361..4720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4809..5357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5387..5515
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5666..5713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5737..5771
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5788..5918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5939..6309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6359..6512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6535..6582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6632..6716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6814..6932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7014..7037
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7111..7160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7174..7193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7202..7257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7269..7289
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7369..7427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7443..7462
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7518..7699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..348
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 465..479
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..520
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 612..631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 823..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1218..1235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1245..1259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1308..1327
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1339..1377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1393..1411
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1422..1529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1600..1618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1644..1659
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1688..1711
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1713..1741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1819..1857
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1858..1890
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1922..1968
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2112..2207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2507..2521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2645..2666
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3114..3144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3151..3186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3247..3262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3271..3297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3344..3368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3391..3425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3448..3468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3477..3496
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3534..3549
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3550..3605
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3631..3646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3788..3813
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3832..3849
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3861..3875
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3884..3898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4083..4110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4232..4254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4385..4420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4433..4463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4481..4516
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4549..4569
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4578..4627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4636..4654
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4689..4718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4823..4853
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4854..4954
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4974..5009
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5022..5065
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5087..5110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5170..5229
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5262..5282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5285..5303
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5307..5357
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5394..5418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5458..5478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5666..5683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5696..5710
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5788..5816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5827..5867
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5988..6009
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6064..6083
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6131..6168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6170..6188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6197..6236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6259..6289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6376..6484
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6496..6510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6543..6582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6644..6658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6679..6708
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6833..6850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7138..7152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7179..7193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7207..7257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7542..7564
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7658..7687
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 7699 AA; 783029 MW; 79622F45DA390CDF CRC64;
MLTLRRFIAK GGVPLILSLC CARSLPPAFL HLYPQHPLVI TLRYVASASS SLPQLLLQLL
LLGRATEKTR TLGDLVDTWR DRWVSTGGVP PPYEPSCVDP PSDQHIDESS VIVSMMSSFQ
QAPLCDDALL QSKDCKDLVS CLQDCSSSLQ VTVMLGRELG QAYYGGTGPG SRASPQQQLY
LLQQLGILFI QLQRVVPWAL KFLYAAAPPP LFMMNETECT LSLLSSKHNA HEHPAIRASK
KLVSSLGSGN TGGGATGGGD PGGVLSSNDM LWSSLVEFAY SVPSSSPVTT EKKKIETGGR
KRGGGAEEEE TAVVKIKEER EVDMDAGADP GGDEEKHQEG RKKIAGDEGD TSSLVPDETA
ESSVVRVEML RGMLQTIRAI VVNASRSLNS NIVRSKKSSP QHQHIHQQVA QMHCLSIGLH
CRDLLLPIPS MPLPTPLPLS RILRMCNEEP FSSEDAKEGR RGEESTTATQ QSYCTKSQDS
RSRAQRRCPD SEGGEEEGQE IEMEGEEGKR GVMGKTKEAG TGDGEIKVVI EGLGVISTLA
YICDVLDWLY KLHVDEKNRG LLLTMTFDAF HKVGGIVELM RVVDYAFGVN IAVHCYFATR
SLRMSTVENS ASTSSASSSS ASSTVETSPS LSGEGHDIVE VDDLFPLFLF EDDDDDEYEP
KDSRKRSEGE ISHLASLLGR FGLKRRTRKI SSGSRFQKKT TKTTGCGMGG VKNEGDGERG
GGEELSNKET GDHVGRGGDG YEDVCHSAEE RREKFVQWIK SMMNELDKVP MDQLATVKDL
ASKSLQCALA YCDKITSWKR CLNSPVSQYM QKHFERPSFY KRMQRDSSSS SSSSTPSSDE
LSSSTGGGGQ GGTSQQTGGG RNSNSNSSSS SSTSSSAGVG DSTQNTVETR NDTDPGGSHT
STSPSSSSSS SSSVPSSSSS SSSSTSQSSS DTSSSSSGQP PQGGESTSAK EGNGRDAPHA
NASSSSHPPR YHFTYSIDEM IKAYQHLQEP SATKNASSSS SKATGGGEGN HEDVSSNCQL
LPHPDFGKCD IVGLLRSVQC EAASHVAVWW ALASKCGAPI CLPDDVPAES REVYVHHPHA
YRSKGDHEGS SSVARKAHQS LSQQQLFAEA MYKDLMADGE VADGIEEGDE EDMMVEVGKE
GGVKMKKKGQ KGERVRSEDW LLGSLLAPFL QRVTGFSHKI TYHLFDTMTP QRRAWIYNVF
VDIPAAVPSP RTGAAAGAGG SSYNSSSTTG SSMRIGGGGG GSGSLSASAR ASHQQQRAAA
QRALMVSQLT DMGFDERLAQ RAVDITNGRS VELAMEWLLE RQGTEELEQE TQQSSNPPTT
TAGPGAQPER GSTPGEVGGG DVSGTTSSSS SNSESQNSGG GEGGARENSS SGTGEGIGSA
GGSGEGENRD QGLRGSPVNT SESQADRNTT GGGEESGDRP HVTGGNESTQ QGSSGSYSSG
SSGTSTTNAD TAATSATTVP TSSVQGCSTG LGGGGEGGSS SSSAPQESFS LGLAFDSSLA
TTPGQPSSSS SASSSSSSSS SGSSSASSSA HRSAAAIAAA AALMGEVGPS LDFFGGLTAT
SGGGAGAVLL SSFGGDDDDD RGSITSRDLA TVRAVLAAVT GRPNTSSSSS SNSGGGGSRS
GGGFFPYGSS SMGSFGGRGI GGGSGRDSSS SSGSRHQQDT EALFAVAASA ALEGNLKLEE
AWGGMGGSGA GSSSSSSSRF SLSSPGTSRL NGSEGRKRVK ERRDTRMMEE EKEKDDGQGA
SRVERRMKDV LRSAWKGEIA IYISDISAKQ LADYLQRHVV TQLIGIACSL PQTVPSLCES
LVKLLGSPLD LCAWREDTDV SRSGKDRRKG TGKAEKERKI EDEAGAKVKK SEADGSKQEG
KQGQGTDQDT SSHSSSGSSS SENTAATGTQ GGGREEGGAQ GGGETSSGES NRHEKRETDI
GPTSPDSSSP PATSSSCSSS SSSSSSSSSS SSSASSTGSS SSSSSPPPSS SSSSPPQRSP
AVVLQELGEK NLFATLHHLA MRLLHLSQMC QVFPDVLSLL PTSSSSCFSS SSSGSFLVSF
LRDVQKNQGG GGDEDGRSHA ARMARCVFLR LRLQQHLYAC CYILAHLLHR KKQGVSMFLA
ALHAVVLSHR RRRVRQSSEE QEEDGGEAKK SLKMRRRRKA STDDEARKGE YEDKERDLNG
GIEEEGQKKR QGGERRNPSD SMASRVKKED DTPPVEEEKE FKKSQKGDMI GQSKSSDFKS
WIATAAASFR DHPLSLFMNF ISTSLYDEAV LGAHHPYFLS ECKGVLFFPD LFYPSMDEAA
KDSSSSSSSF FIPKTVMNSR GGASASINAC HVIKSPSFPP NSASSTTNIS SSSSCHSASL
PPLQQQQGGG GGRSSSAVSY PCYGCTNLSS SSVVPLPSWC LLDLPPTAPS SSPSSSSSSG
FHPDPKILSI LPFSNLSPQD IQPSSSSSLT SSSSSPSPTL MSSIPLGARP APFLLPALLC
LQELLPLYLL HERVNSLHGT SSPGGAGKKG GSTGRGAGGG GGSSSEVHNR GLGSSTSSGS
VSKGFGAAGV GVVASGDGEG GVMSSSSPPP PPDLRFGSSS SSGVPSPALS KGGSSGIEAE
EDLHHEGLVG TGVFSSVHAG DRSTGGGGAG TGGGGGGEEE RDDCSLVVQS RGHLGGVAGI
EGGTVAQSHS RSTSSEGSVA SAKGRVLSSR EQQELVTACL DTVHYFPGLD GDLMLLLLQI
LQHLTIVPSN ALHLLVYNPK RGGAEGGGAF LTCREALSST CITMMRGRTQ QGQCADSRRV
KKEDLHAAID VRRGMGEEPT TGDEADGQEA SMDEEGFVSS SQWMITKKKK MFSSFSSSLY
DPASSSSSDL PFFSVACTLL SSLYPRSSTM ITTGLSHKYL PYPSLFASIA SSLSPVERKM
LLQRKKMTDR FSSHSKPVQP GGEQASEEER EEQQQPQDPG TLRQRGADQS DSVIPEEEES
LRGSGGGGGL GVLLRAPRTA SCNGMLSLIQ QITCHICEDP SILTAFIENE VQFIFKRASL
VARSLYRRVH GVPPPSTDDP LPFLMPAEAV LSQLSPFMQR APLLVEQVLK ACCQVCTTAL
PPSSSGGTAG GSGGERKTDL SEATASHHSA TSKGTTPRGR GGKGDVGGGE PEGENKMTSS
SSSVDPSLNG SSSGKTSERS RSGSFLSLGG ERGEVSSSSS SSRSSGGGTR LRPHSDGGSR
SQTARSLPQG REDKRSPPTP SSGVCRAGGA AGSSGEGQTG EGGSAEERMM GENDATGASS
SSPASSGVER ERREDSHADH PSSSRTSEQS GGGENKKEKE GKDGAEGEGK KKSLKNSSLT
PHTDTTGMTA SPREEERHPI LCGIYIGPKK GFVFKKGDRG LGYYPLTSTS SSSQTSSSSS
PPSRPSQKSP RDSQKKIHST PPTAKTRGGG KHQAKRGEGR PVGGDEKKEE EEGRGGRKGG
EEEEEQGGQQ QVPGEEVILL RWLHDNERSQ TSLSLHQPPS SPSTTSPAAF GGGVGGGSSV
SHSSSSSSNQ RRVKRLLSQA QRAPQLALVV MSLLTDYAGI MLNLEAMTRL TGASLQQQGP
PLSSSSKGEG SEEDVGKKGA RGDGLRNSEE GEPSRGDGEE GGRREKGQES HRKKSEKEGE
EEGNAWRSLE SVLSLPLQEK TSCSSVVKRG HGFSEHTDQE QGGKEFDMTD GEEEEGSDGE
SYRRKKVMNH SWMSGIRPMY PFALTADSIL YIMVQIISCY PSVLPLMLKS VPITQLSSSL
LFPCLSSHLW TTKAIPPSSR VVSGGGSAGD LHSPQPQMPS DVTAVAAGGG GEGVSTSCAV
APCGDRSTSL ISPSSSKPTG VMSASSSSLR GRGGATSGDA PVAAHKGSGG GGSYHRSSTT
TTTTTSGGGG GVGLGRGHVH QPISHRSHSL HSQLHLHMKG KPTASSSDGL SSLSMESNAL
HPAPGVSMDV DSSSHSTIRG GGGPPAVGAS AGLPTIGSCG GAIATGGVGH DMVRLYIPQS
PPWSFTSTSC PPLLSSYASS LGGFISPTTT GAPLTSTTPL TAHSSYQTAE GGMLHVNSQS
QAGHSHLSMS PRGEIPSSSL LPSASSSMTI ASSKLLGGGT GEFVLASPRT TPTGGIGGEV
GGGSGSCTSS TTSSHGIRTT HSSSSSSSSS PLNAHVVVVV IRPLLEYLLR EILPRVLTLT
LPPFAATDKV YHRALKYQRE GRLISMGSNL CYQGGSPAFV TLNHLIQVLG AMACFSYDIR
RILLQQVSTC LGSLSRGGGG GGAALLSSLS PSFSSTSSGG HRGNLNSLTT SNRPHPHLHS
HHSSGLHAPP FSNLPLSSSS SFRLPEGREH SKGAAGLQYH QHTLRNSGGG VDSACSSSSS
TSSSLSPLPS DLQVTAFYTL CSILYRLFTL PADLPPNPLL VVSSPGSQGG SGGAGGGHDS
HANNAPGGGA SNTHQSNPSD KSSQIGAAPA GGSSTCKGGS GEQGGGPHSN GGDGEGGSSS
SSGSGSSSSH NSSGNSNSGG GGGTTGGRGR GGGGGGGGTT SGVGRSASSN PTDAGGGGNS
SSSNRNGNSR QGGSGENHEA SGGGRHEINE RTPLLQSPPL PMEIDGEEES MMTTSQQHHN
NSNGSAGSSA LGVMGEGGDS SASSSIGRHN RNPRGTLDPG SQRTHSTTNS QTNSHTHPSS
NTSGGGGGGS RGGGEAGSFS SCTTSTTAIH TGGGEGSSGS GDGGDDPPRR PPSSGGLVGG
GCKNDGVESS HPAVSNASSS APSLAVGRSS QPSNEKHSIK GQLGLGLDDL QRLRDSLSLF
LFQLPLFGEE AAAAATMAVR CLAQLTSPEV LGAGGALGAL GGGYHKGIGG GGRGEMSSHQ
HGKHALVGGM IGRRGSSSAD QGGSRHNRRR EDDESEVGRR GGGRVRSTRR GSVEEDEEDE
EEEEDEDEED LVFLDEEDED EEDEDEDMFE EIGEEDDWEE EEEGEDVGEE DPFDDIDEDE
DLGDEGEEEE EEEDAVGLTD DDDVDGDSAE SEEEDAGTGG GGGGLASTRE LPHEVEEEED
DLLLPEPVEG EEEDEEDEDD EDDEDDDDDA PRIRERGDLD YAEMMEEDED SMGDPHELEE
EEDEEEEDVM MDEEEEDEED EEDLLPTSSS ASRRRRDRRR RRRPPPTSTT TDTLEETAAG
DHSASPNSSA GGEGGEERRG EQGSGAHRQP GDTPEAEQAE RNDAAVQGEG GTFSSFDSRR
SGEAATGGDR SASVETSADT SATTDTQAPD HTSGQTSSSS LPSTGGGGGR DEASLSSSSS
SSAGVSTGGL STGGVPLRIP DDAEGGEVQG SPPDGESNRH RDASTSGLSF IASRSSGTGR
SPPSGGGARP PPPPPPPPPL FGAVNVPDLD DDEDEDDEDE EDDLDDDDLE DEEDLDEEED
EEEDEEDDDE DEDEDDSLDE LRFHFHLSAD AHQDLVSAVR GVVASAASAG SGSGGGVGGS
SSSGHHRGRN STSGGGLGGG NGLISIEDDP LGAFEPLPSS SAISGGHPHR AGGTGGGGGS
GSSHTGGVGV TLSSSGARGG GNGGHHHVSS SGGTGGGGGR GMMGGRGGDR GGGGGHLLSS
LLGGLGGGAG AAGGLLSSGG GGLFSPQLIF GSGIGSSSGS LSISPLLTSS GGHPATFGML
IGTATTGGGG GGGLIGNIAS SALPFHFSTS SSSPSFLDTA SNAGGWNSAS GQGGMFLSSS
SIAGSQQQWS HGDAFSIPGE HPLFASACNS SSNNSSSSNS GGGAGHRHLG GSSGGGGGGG
STTTAASPYS LGGGGSGGPS GIIGVLGGGS GGSGSSFTAR LAGGSSQGGR GNAVGRGGSA
PGGGRSSSPN LQEERRFLQT ILDRLVADTG DSEGEGRHVH EASRSTQRRE GRQEVARGAA
GGEGGSGDEN HGERRRERPS EDRRSTRGRD PGSREGGGRR RGSEDEGSSR STVTPPPATT
TTGGEGGGEE YCACLGSPGS GGGYSDSDDS SLDFFLVEDG GHEQQHRLLT SALISRLAST
PGGGMLQTVS EISFPAVPEE PSASRENESQ PTESVAGGRG GGGGTSSARR RRGEEGGEGD
RRREGESSST APGREGTRGG EQGREEGAEV SSSSASQEAR PPPSAEHAEE GGSAGGSGEA
TVGGDSERAR EDHEMDVDTE EGTGGAERPS SSSSASAEGG GDVPGAGGVV EEGGEGRSSS
GASLPAPASD EARRAPEESG EAPVEPMEIE EEQRPHPGGG EGGEMEQHME EATSSLTGEE
TDDSLLQRAI QASLALGGGE AQSSTPGGTS QRPQQQSSSG SPLESDSTTT VRAGVTASSH
GGGGEREERQ GEGGVSTEEG GHPQQQQERE STQTESSNSQ SAGEEQTQGS PPTAPPPQEE
EEVECATSGG ILNPLARALG LTEAQLCDAA GMDPSFLEAL PDDLRQEIVI QQLRQLTIQA
VEARRRPPPS SSSPAPPSSS STTTTGPSAS SSIPSATAID SSPASSATSG GESHSTAPPP
TDPHSVSSSS SSESSAAAHE DSRSSPTAPG PASSSSSQET GGVTGEGETQ QRSSSSSTDG
VSSAPGDEVS PPQPRPSVSG GRSLSSSPPA LNEIRHEYLD ALPSALRQQV IAACRSPGGT
GAPHESSAAS GQGGGSSAGG DGSGGGASSS SSGSSSSTGG GGGTDLDNAT FLATLDPLLR
QEVLLTAGSD FLRTLPSEIV AEASLLRERA LQRQHHHNRS QQHRGDGGQS SSRHQGRRGA
SGSGARQGGG GGQGHGGGIL FSRSSQHQGG GGNTGGGSSS TGSSGIGLGG GQTGGGGGGR
VYAVDIMRGG GGTGFDGGRG RNTGGGGGND GIVVGGMVSP PVFTFTSRLG GGGLDGSGGG
GDGGGGEFGA LTGGDMYLAG LFDFLDMQIL QAGGGSSSGG RGGNRGGGSL GAQIFGLTSQ
GSSPSLEDSF FVGQSGAGGG GGSSSSGRRR DRAGGRGYHQ SSSNGIGGGG GVSGLLLPHH
HHNDGIGENS NNILLHPRHQ HHRGGSSSSN GPFGSSAVER FLNGAWAAAA AAAAAATTGN
SGGGGISVGG IPAGTAQGGG GSRGGGGGLG ASGNSGGQYN ASSSGLWTAT GGGGGGYGST
GTTSTTSSPY GGRGGHSHQT NSLIAFLSSA TGGGVTGGPG GLITLTPAPF GAAGGATGLL
GTISLRSDGV IDGLSVLNEW LFSSAVGVGG SSSSASSGQG NSSLLGGGGG GPAASGGTSG
GLQATTAVGG SRGGSLGSGG GTWLTEAIGG GYRASGGGGW NAASTSTTSG STHAMIGTED
HVHTTRGGSH TTTTDASSSS TSGGAATGAA GGESQTATAT TTTIATPHSS TPPQTRALQT
TSLGTASSLS AESGMVGGGS RGAGGGGAGG GSGPRLLYGV YRPPRPPVHP LGVLGICRLF
YLRRELNRKL FFTLLYNVAS AHQDSWHLLV LLFLVICWSA APDCQLLPHQ TTSSSSSSSS
SSTTRTTVPS LVQSSGGGSG PSSSSSRAPP SSSSLPTSSS SLSPPLSSVG FPPTTLYGPL
SDAQQQSLVG GGGSSHLSSS SLLAQQTTTS SIVLAFERPS ASAVATERVL EQLRSILTVL
PSASYAFARR MRHPQAVTLK DISYPPSATP QRPAGGGGTG GGRVSGSSSS GSASGVSSST
CVVAGGSGGG GPGGDENDPF MNSHPNNSHR HHAKKHHHLE GSGGKKDRLP SAGGGGGAGS
GRRLSDSIDG SSSSRGEGGG EGREKISTGG GVGGKKKTEA PQQNNNVHEN EETSATSNSN
SSSSRHPLVK APHDRSSKA
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