ID   A0A2C6KTE9_9APIC        Unreviewed;       777 AA.
AC   A0A2C6KTE9;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   22-FEB-2023, entry version 17.
DE   SubName: Full=Had family iia protein {ECO:0000313|EMBL:PHJ19453.1};
GN   ORFNames=CSUI_006715 {ECO:0000313|EMBL:PHJ19453.1};
OS   Cystoisospora suis.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Cystoisospora.
OX   NCBI_TaxID=483139 {ECO:0000313|EMBL:PHJ19453.1, ECO:0000313|Proteomes:UP000221165};
RN   [1] {ECO:0000313|EMBL:PHJ19453.1, ECO:0000313|Proteomes:UP000221165}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wien I {ECO:0000313|EMBL:PHJ19453.1,
RC   ECO:0000313|Proteomes:UP000221165};
RX   PubMed=28161402; DOI=10.1016/j.ijpara.2016.11.007;
RA   Palmieri N., Shrestha A., Ruttkowski B., Beck T., Vogl C., Tomley F.,
RA   Blake D.P., Joachim A.;
RT   "The genome of the protozoan parasite Cystoisospora suis and a reverse
RT   vaccinology approach to identify vaccine candidates.";
RL   Int. J. Parasitol. 47:189-202(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHJ19453.1}.
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DR   EMBL; MIGC01003435; PHJ19453.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C6KTE9; -.
DR   VEuPathDB; ToxoDB:CSUI_006715; -.
DR   OrthoDB; 217676at2759; -.
DR   Proteomes; UP000221165; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 3.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006357; HAD-SF_hydro_IIA.
DR   InterPro; IPR023214; HAD_sf.
DR   PANTHER; PTHR19288; 4-NITROPHENYLPHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR19288:SF46; HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF13344; Hydrolase_6; 1.
DR   Pfam; PF13242; Hydrolase_like; 1.
DR   SUPFAM; SSF56784; HAD-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000221165}.
FT   REGION          1..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          478..508
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          632..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..45
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..82
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..121
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..142
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        143..158
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        188..217
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        218..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        662..680
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   777 AA;  86323 MW;  460DED424CB8D8AA CRC64;
     MGRLSTGAAQ HPYQQLYSSS SPTSLCVSPF KKEHEGSNQN GMASSNKEKK RNRSLSSATK
     NISSLSLQPS GKSQLSNRAI RKSQKSRQSH STTHHVDHPS LRLSPSSSFS LTSSSPSTFL
     EPDHLRQEDA ETCGTSFKLS REKRSNKKVR KTLHKYDKRL SFRRTSLIPK ATSDKKTAPS
     QNGERHGCLQ GDIEKIQEGR KKHHEEGRHK SNEKRGRRSP SSCSSGSSAG ASRSKKERSS
     LVTPSSSFIP AKEQEKIASS SSSFALLSSS SSSRRGTKKE GETKMRERHL SSLSDFCWFQ
     EKCLCIESLS TELSRQLPQI SPSRFVEKQR EYLSFLKDHA HLSSCTSKIL LSQEDYQKDF
     LDHYENFIFD IDGVLLMGKQ SYTGISNTLQ LLRLRKKTIL FVTNSASKSR RICAKVLTDA
     GIQAYEHEIV TASYAAAQYI RETYPDVKKV FMIGEEGLKE ELNLAEIQVV SLDTHPLPTS
     QTSGVSTPQQ QQQSRTPNTH SSSSSCDGRG VISIESEADF RSVSGCLDPS IGAVVVGWDR
     RLSFSKLCLA SLYLQRKIEN SKHISSSSRE NSDGFLPFIA ANRDSYDMVE AYKIPANGAA
     VSYLEAASTR KATCVGKPSE WLARWLVSRH LPSPSSSEEE AEEEDQPILD RSNHSNSARD
     GNDSLKEQQT SLQASCKQNG VAKNRKKKKK GGVEENKRNL KKTVVCGDRL DTDIELGHVM
     NVDTCLVLTG CTNLDVFLKD LIFPQLQTSK RDKKKHSNAS FPTLVLPHLG ILAQDQL
//