ID A0A2C6L6I7_9APIC Unreviewed; 625 AA.
AC A0A2C6L6I7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Bromodomain-containing protein {ECO:0000313|EMBL:PHJ23064.1};
GN ORFNames=CSUI_003089 {ECO:0000313|EMBL:PHJ23064.1};
OS Cystoisospora suis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Cystoisospora.
OX NCBI_TaxID=483139 {ECO:0000313|EMBL:PHJ23064.1, ECO:0000313|Proteomes:UP000221165};
RN [1] {ECO:0000313|EMBL:PHJ23064.1, ECO:0000313|Proteomes:UP000221165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wien I {ECO:0000313|EMBL:PHJ23064.1,
RC ECO:0000313|Proteomes:UP000221165};
RX PubMed=28161402; DOI=10.1016/j.ijpara.2016.11.007;
RA Palmieri N., Shrestha A., Ruttkowski B., Beck T., Vogl C., Tomley F.,
RA Blake D.P., Joachim A.;
RT "The genome of the protozoan parasite Cystoisospora suis and a reverse
RT vaccinology approach to identify vaccine candidates.";
RL Int. J. Parasitol. 47:189-202(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHJ23064.1}.
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DR EMBL; MIGC01001326; PHJ23064.1; -; Genomic_DNA.
DR VEuPathDB; ToxoDB:CSUI_003089; -.
DR OrthoDB; 152619at2759; -.
DR Proteomes; UP000221165; Unassembled WGS sequence.
DR CDD; cd04369; Bromodomain; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR PANTHER; PTHR24184:SF11; ANK_REP_REGION DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24184; SI:CH211-189E2.2; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000221165};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 151..183
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 184..216
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 586..625
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 309..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..348
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 65978 MW; 030FB5A91683D5CD CRC64;
MMNASMSSSP PSPSPFLFLF RIARFEPIET VFDSLTKALD QHLHDLQVEN PSLSSSPEEL
KEYQRKVICE KELFVDPHSR ATLLFEVAQR EKDDEAVKLS QYLIEDLKVL TPDMRDRMHQ
TCLFYSAREG HINLSHYFIQ HGCHPNLQDS VGQTCLFYAA REGRSTCLST IIDHGGDPNI
LDINKQTCLF YAARDNRLEA VKVLLEKGAD PYIKDTLRKT AWHFAKSNNH LAVCTLLKNY
TGGGGGANSS SSSNHAASLL MNSSNPGGGI TTSCSSSFSS LTGGAGVGGR TCSSSSSISS
YSSFTGISPT TTGLPSSSSA SSSSLGGGGD NSHAAGLLQQ QGSSSLGPGV ATGGGDKKGN
ESHLSLSLSQ GGGGAHQLHE DYANHHMKGG RIGGGGAAGG GGRGKNVGGK AGYFPPGLSA
GGGGVCTLNG GGSSTTSSGS GSYSHFGVST GVDDIHHLHH MQRKKYRLQF QPLPEECPDL
WLFAGSDKLT EFERLFPSLA VWRREETGDA TSTGVVGEGL GGVSTGAEGE SLMKVESAPK
TAKDHYDALH EALRQNSSYL AGGGGTGMDL LSSWQTAALS LLSELSKYEG GHIFEKPVDP
KTAPGYYDIV THPISFSCIK AKXVR
//
