ID A0A2C6LB94_9APIC Unreviewed; 1020 AA.
AC A0A2C6LB94;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Tetratricopeptide repeat-containing protein {ECO:0000313|EMBL:PHJ24362.1};
GN ORFNames=CSUI_001791 {ECO:0000313|EMBL:PHJ24362.1};
OS Cystoisospora suis.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Cystoisospora.
OX NCBI_TaxID=483139 {ECO:0000313|EMBL:PHJ24362.1, ECO:0000313|Proteomes:UP000221165};
RN [1] {ECO:0000313|EMBL:PHJ24362.1, ECO:0000313|Proteomes:UP000221165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Wien I {ECO:0000313|EMBL:PHJ24362.1,
RC ECO:0000313|Proteomes:UP000221165};
RX PubMed=28161402; DOI=10.1016/j.ijpara.2016.11.007;
RA Palmieri N., Shrestha A., Ruttkowski B., Beck T., Vogl C., Tomley F.,
RA Blake D.P., Joachim A.;
RT "The genome of the protozoan parasite Cystoisospora suis and a reverse
RT vaccinology approach to identify vaccine candidates.";
RL Int. J. Parasitol. 47:189-202(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PHJ24362.1}.
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DR EMBL; MIGC01000709; PHJ24362.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C6LB94; -.
DR VEuPathDB; ToxoDB:CSUI_001791; -.
DR OrthoDB; 204321at2759; -.
DR Proteomes; UP000221165; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR031101; Ctr9.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR14027; RNA POLYMERASE-ASSOCIATED PROTEIN CTR9; 1.
DR PANTHER; PTHR14027:SF2; RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000221165};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 972..997
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 678..711
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 712..745
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 846..879
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 257..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1001..1020
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..527
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..592
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1020 AA; 111637 MW; 114D7AE2AA2D84CF CRC64;
MTSHIDRSPA AACSVGSSRR DLAKPCPGSA GRKKLEQQAR LLTIDLQGGR RADTPSSDVL
DRTSVCSSVL EDTGRHRYAV STSSSAPRGT PYSTRSAPNL HLGRPENSGC VETADYSSSI
SSRSRERRSD NTAASTRSLV SSLLMPDGVT VRAPATLGIS SGDPIGTHIL KRRTSCLTSE
TFSPAGPFTS RLNLSLHRRS LNSTWHQTFR SSAATQRTRR PRRPADSEND LLPKLTAFSP
SLNRALSQDA ALFPIRTSSD SVSSPSSSRV GGTPASELPS ETPLTSSGLL QVPHVAIAPN
KQVNTSTSPA GSADDSSFAC AGRPPTACVV LRLPPAEGDL AQPARLSSDP PPAQEAGFSL
DVGVPTPVSG LDSRNSGLLA LAEVTREWTE TPELFREGSE KTQSSVEHEF FPGHGALLLE
EEVRKETAKY EAELKKNPRS EDALYQLGVL QFRDGKAELA IQRISEFLRS PAVSVRSGGD
LSEPLALPAS EGIVDCEHEG VSGERESRRW ARASDREDNE AVTKESSRHP LTRALPVAPD
AEHEGQAAHI AEGTPSKQED KRDEYADQGE ACETKTAGGR SKEKEELPRR GSDAEGGLFL
AGQKGRQRDK LAVDKEASLD GALQGQQKDG NNGREALHSR FGRAVPIQKL FNVILDRRSQ
LDRRAKDILA GWGPPVYLQL EKLLGHLWFE QENYAEAIRH YWRCVDICPD DAQLFTNLGL
AYYEMSAMKE ATAAFEHAIR LNERDVTALS VLAMLLMDEF AEEEEEKLRV LEEQEEEVVL
PTDEDRLKHL REGTERCVMM LRKCLEIDGN NILAQLHLAQ VYMYREEWER CEEIFEALLK
ENADDTHILN NLGQVALHKG DTQGARRLLG RVLEINPKDE LAHMHMCELL CKDNEPTLAL
EHFKLCCESS PDSVSLHATC GLPLCEVGKE KEVIAAYTDF IKKHPGSAAA RAFKRSLGSI
GEDVGFFEST TIVIFIVLPI VLLIVLLLAC AHFFSVWPAS DASQQSSPSR AVSYSDHSEL
//
