ID   A0A2C6LBG4_9APIC        Unreviewed;       810 AA.
AC   A0A2C6LBG4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Nucleoside diphosphate {ECO:0000313|EMBL:PHJ24384.1};
GN   ORFNames=CSUI_001756 {ECO:0000313|EMBL:PHJ24384.1};
OS   Cystoisospora suis.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Sarcocystidae; Cystoisospora.
OX   NCBI_TaxID=483139 {ECO:0000313|EMBL:PHJ24384.1, ECO:0000313|Proteomes:UP000221165};
RN   [1] {ECO:0000313|EMBL:PHJ24384.1, ECO:0000313|Proteomes:UP000221165}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Wien I {ECO:0000313|EMBL:PHJ24384.1,
RC   ECO:0000313|Proteomes:UP000221165};
RX   PubMed=28161402; DOI=10.1016/j.ijpara.2016.11.007;
RA   Palmieri N., Shrestha A., Ruttkowski B., Beck T., Vogl C., Tomley F.,
RA   Blake D.P., Joachim A.;
RT   "The genome of the protozoan parasite Cystoisospora suis and a reverse
RT   vaccinology approach to identify vaccine candidates.";
RL   Int. J. Parasitol. 47:189-202(2017).
CC   -!- SIMILARITY: Belongs to the NDK family. {ECO:0000256|ARBA:ARBA00008142,
CC       ECO:0000256|RuleBase:RU004011}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHJ24384.1}.
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DR   EMBL; MIGC01000705; PHJ24384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C6LBG4; -.
DR   VEuPathDB; ToxoDB:CSUI_001756; -.
DR   OrthoDB; 5471350at2759; -.
DR   Proteomes; UP000221165; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR   CDD; cd22970; DD_NDKH5-like; 1.
DR   Gene3D; 3.30.70.141; Nucleoside diphosphate kinase-like domain; 3.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR034907; NDK-like_dom.
DR   InterPro; IPR036850; NDK-like_dom_sf.
DR   InterPro; IPR001564; Nucleoside_diP_kinase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46161; NUCLEOSIDE DIPHOSPHATE KINASE; 1.
DR   PANTHER; PTHR46161:SF3; NUCLEOSIDE DIPHOSPHATE KINASE DDB_G0292928-RELATED; 1.
DR   Pfam; PF00406; ADK; 1.
DR   Pfam; PF00334; NDK; 3.
DR   PRINTS; PR01243; NUCDPKINASE.
DR   SMART; SM00562; NDK; 2.
DR   SUPFAM; SSF54919; Nucleoside diphosphate kinase, NDK; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000221165}.
FT   DOMAIN          132..280
FT                   /note="Nucleoside diphosphate kinase-like"
FT                   /evidence="ECO:0000259|SMART:SM00562"
FT   DOMAIN          283..422
FT                   /note="Nucleoside diphosphate kinase-like"
FT                   /evidence="ECO:0000259|SMART:SM00562"
SQ   SEQUENCE   810 AA;  90582 MW;  2F51562F337868C8 CRC64;
     MAVTHRGDGS LLIVLPDVVR AEKLPSVVDA LLDQDFDIIR EKEFCFTHEE AETFFQETPA
     SQERSEFLDQ VCSGYVRLQV IQHPKGRTAA RLREFVGPES LEQAKEAEAA GNTNAGVCVL
     SQPLFSVDKC PVERTFALIK PDAVAAGVCQ QIEDEILDAG LLIICRKHVQ VTEATFQALL
     LSLVFHSLGS RSLIACPVAM VLEGRAAIRR WRLLCGPTDS NFARRVGKWT LRARFGTDST
     RNAVVSSKRC AGCISVPKGH GSDCAERVER EAFIFFDNHD FDLERTFGII KPEGMEDSVR
     CAILEEIRNN RLQIVSQKEV LLEKERVLDL YQVHKDKPYF NDLVQYMMSR PVMVLILMRV
     GAVRVWTDMV GKRSDMGAAP RKKSLRGRFA TDKLRNVVHA SDSAVSAEQS ISFFFSEVPL
     YPVPTTDYTH DYIFCKRAAF GRQIEHTPPS QDGVTPTLQL LISKGLEEMC AVKPLGLDAI
     SWLADWLERN SAKPEDAPRL AVEPPEHSKN RIITVEPGQQ APHIILDPPT NRPYTYVRLV
     GGPLSGKKTL AKKIAEETGY CSLSFNDLAN KEIASKSAVG QLLEPLMRGN LTPPLTLQSK
     VWKRAFAAKE AVTRFVVADQ IYTLEQAEYF DKELGPPEFT IVLDCPREVI LSRAEMTSDD
     DVTDLEEQVN NSLDHVADIK AHYQRIGKVQ VIDASASTSE IFQEIRHLFF PAVTYLFAHP
     GIDVNEITTK LQEGFGFKHV DVRSLLQESS RTNPSLYQTL ASGATPAASI VCPLVIDKLK
     ELRAAGQDHF LITEFPRTLK QMRFVEEKTR
//