ID   A0A2C7AE63_9PROT        Unreviewed;       326 AA.
AC   A0A2C7AE63;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:PHK95364.1};
GN   ORFNames=CR162_09075 {ECO:0000313|EMBL:PHK95364.1};
OS   Pseudoroseomonas rhizosphaerae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Pseudoroseomonas.
OX   NCBI_TaxID=1335062 {ECO:0000313|EMBL:PHK95364.1, ECO:0000313|Proteomes:UP000223527};
RN   [1] {ECO:0000313|EMBL:PHK95364.1, ECO:0000313|Proteomes:UP000223527}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YW11 {ECO:0000313|EMBL:PHK95364.1,
RC   ECO:0000313|Proteomes:UP000223527};
RA   Banno H., Chua N.-H.;
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PHK95364.1}.
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DR   EMBL; PDNU01000012; PHK95364.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C7AE63; -.
DR   OrthoDB; 9808822at2; -.
DR   Proteomes; UP000223527; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000223527}.
FT   DOMAIN          218..309
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   326 AA;  34542 MW;  F9E213D309A27E51 CRC64;
     MEDAAEFILL AGFLGSGKTT LLVDWLRLPE AADTAVIVNE AGQIDVDGAV IATGGTLPMA
     LLSNGCVCCS LTNDLVFTVE ALLRQRMETG KPPFRRIVLE CSGLSRPGPI LRSLGPLAPL
     GLRVRVVATC DAAQAAERAA HFEEFAAQLA AADTVVFTKL DQTSPEAAQA LAASINPLAR
     AVVEPDRAAR ALAAFTAPPG RASSLPEGEA GAHPRVSVLL ARFTPEASWE DRLDWLENLA
     AFAGERLLRV KGFLHPPEQP GLAVLVQGVG TLFSPMVPMP RGERTPEALV VILRDLELEA
     VRQMMPEAPA WISRLSGNRL HCAGVG
//