ID A0A2C9C3M8_CAEEL Unreviewed; 293 AA.
AC A0A2C9C3M8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=PDZ domain-containing protein {ECO:0000313|EMBL:SOF58868.1};
GN Name=mics-1 {ECO:0000313|EMBL:SOF58868.1,
GN ECO:0000313|WormBase:T21C9.1b};
GN ORFNames=CELE_T21C9.1 {ECO:0000313|EMBL:SOF58868.1}, T21C9.1
GN {ECO:0000313|WormBase:T21C9.1b};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:SOF58868.1, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:SOF58868.1, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:SOF58868.1,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; BX284605; SOF58868.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9C3M8; -.
DR SMR; A0A2C9C3M8; -.
DR EnsemblMetazoa; T21C9.1b.1; T21C9.1b.1; WBGene00011890.
DR AGR; WB:WBGene00011890; -.
DR WormBase; T21C9.1b; CE06471; WBGene00011890; mics-1.
DR OrthoDB; 2878025at2759; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00011890; Expressed in embryo and 4 other cell types or tissues.
DR ExpressionAtlas; A0A2C9C3M8; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF51; DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|EPD:A0A2C9C3M8,
KW ECO:0007829|PeptideAtlas:A0A2C9C3M8};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 268..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 73..145
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 167..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 293 AA; 32336 MW; 2D0011DAC33FE806 CRC64;
MMVSPPQEDT VFNTDSDPVY EHHAALVSSP FHADEDHTFD ISFAAEATDD MTFNDTTTDG
NGQESVPLEA LTVVEIEKTS KGFGFNIVGG TDNPHFVGDI GIYVSSVNSE SKSYGVVRTG
DKILSFDGID MTYKTHDEAV EVFRSVKIGH VAKMLIDREY LHLQEDRTQT PTASVSITPQ
VTPQTRSTQN NTDTPKSMSH SESKSRLTSH GLSAVIERIR GKVYEEEDAQ SVTSYAPSTH
SIIDDVPRTP RKPLSLLDPR NNSWLTEALY VSIGLGALTI SGYLAYRFIR GRR
//
