ID   A0A2C9CE22_KUEST        Unreviewed;       708 AA.
AC   A0A2C9CE22;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN   ORFNames=KSMBR1_1337 {ECO:0000313|EMBL:SOH03838.1};
OS   Kuenenia stuttgartiensis.
OC   Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC   Candidatus Brocadiaceae; Kuenenia.
OX   NCBI_TaxID=174633 {ECO:0000313|EMBL:SOH03838.1, ECO:0000313|Proteomes:UP000221734};
RN   [1] {ECO:0000313|Proteomes:UP000221734}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Frank J.;
RL   Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; LT934425; SOH03838.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9CE22; -.
DR   KEGG; kst:KSMBR1_1337; -.
DR   OrthoDB; 7052926at2; -.
DR   Proteomes; UP000221734; Chromosome Kuenenia_stuttgartiensis_MBR1.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR024163; Aerotolerance_reg_N.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR011933; Double_TM_dom.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   NCBIfam; TIGR02226; two_anch; 1.
DR   PANTHER; PTHR37464; BLL2463 PROTEIN; 1.
DR   PANTHER; PTHR37464:SF1; BLL2463 PROTEIN; 1.
DR   Pfam; PF07584; BatA; 1.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000221734};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        57..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        686..705
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          93..277
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
SQ   SEQUENCE   708 AA;  79540 MW;  44B998C1B81008C5 CRC64;
     MISFLNPLLL FGVLGACIPV IIHLFNKKKA ISHRFAAIDF LLQSNKRIYV KFKLRQLILL
     ILRACLFAFL AMALARPFVK NIGGGNDGKN PTSNVIIVDD SYSMQYAEKG KPLFHAAKNT
     ARNIIGQLTK DDKAAVIGCS LANSMIVPEL EYDKENLLTV IENLRPGYST THITSALDRA
     IEILMSDETP IKQIFIITDL TRNGWDLKWF HDGQQKLQNN ITGVHIINVS EGKDYGNIAV
     TGLEFQNNVF NKSGDVSFKA TVSNYSPVKI KNLLAQVYVD QKKVVQGFFN IEAYSQEVKE
     FSFKVEKGNH FGWIEIPEDN LIADNKRYFA INEEQKLDVL LIDGDPKTNI YESETFYLEK
     ALNPARGHVS SLKPVICSIH EVEGMVFEDF DIVFLCNVEM LPYEKIEELE RFVKDGGAVV
     FSLGDKVEGS YYNNSFEALL PHRLYTKKIF TGNVLITEEQ PLSLKISGVM HPAMRFLSET
     NINMLTSVSF HQVFYVEPAP LEGAKTVLSF SDNTPAIVER QVGKGRVALI ASSIDRDWTD
     LPVKPLFVPL IQQLCRYISG STTGETKQEI LVEQNWQFPA PYDVGNLETT NPGGVKTLLP
     PQVINNEKYF VYHETHLPGV YSFLINDTSQ QQNLFYFPVN VDASESNLEK ISEKEITALM
     GETNVMVRSS SSGERREVVR GEAKTTLWGV LLLLALGILV AESFVSRK
//