ID A0A2C9CH87_KUEST Unreviewed; 1193 AA.
AC A0A2C9CH87;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=KsCSTR_44950 {ECO:0000313|EMBL:QII13874.1}, KSMBR1_2528
GN {ECO:0000313|EMBL:SOH05015.1};
OS Kuenenia stuttgartiensis.
OC Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC Candidatus Brocadiaceae; Kuenenia.
OX NCBI_TaxID=174633 {ECO:0000313|EMBL:SOH05015.1, ECO:0000313|Proteomes:UP000221734};
RN [1] {ECO:0000313|EMBL:SOH05015.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Kuenenia_mbr1_ru-nijmegen {ECO:0000313|EMBL:SOH05015.1};
RA Banno H., Chua N.-H.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000221734}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Frank J.;
RL Submitted (OCT-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QII13874.1, ECO:0000313|Proteomes:UP000501926}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CSTR1 {ECO:0000313|EMBL:QII13874.1,
RC ECO:0000313|Proteomes:UP000501926};
RA Ding C., Adrian L.;
RT "Newly sequenced genome of strain CSTR1 showed variability in Candidatus
RT Kuenenia stuttgartiensis genomes.";
RL Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP049055; QII13874.1; -; Genomic_DNA.
DR EMBL; LT934425; SOH05015.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9CH87; -.
DR KEGG; kst:KSMBR1_2528; -.
DR OrthoDB; 3272385at2; -.
DR Proteomes; UP000221734; Chromosome Kuenenia_stuttgartiensis_MBR1.
DR Proteomes; UP000501926; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR Pfam; PF13426; PAS_9; 2.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 3.
DR PROSITE; PS50112; PAS; 3.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:QII13874.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000221734};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 314..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 338..390
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 395..452
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 471..523
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 542..579
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 615..667
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 830..902
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 907..959
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 972..1185
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 1193 AA; 134616 MW; 251B87F343F9EF00 CRC64;
MFRSIRIKLI FFFLLAVLTP LLVMRLIAYP TARKAIHETT INNLQLITSK KAFLLNDRLK
KIRRDAEHLA KNPFMAAAVC LAKADNTTTT RFVSLLSTEN NLHEFIISDI DGNICVSTDG
SIIGLNIAGS KGFLQAGGGE ICFSETPPIT TFDTLEAQNW QAIFNTLYAY IPIKENGHIV
GIVVLKSDLS FLSKEILEIP HGDNYAVHII NREGQFIAGL APGKLLHTTG NFAKEMPLKT
LLTEPGTNQF TRSVKACLAG ANGYDMIGYV NNAGKTVLGA WHWVPELQWG IIVEVDADKI
SLVMNELKNS ISKILSYLTV AGIIMAISGI AFAFITGQKI GTPILTLTKA TRKMSAGDFS
QRVEINTRDE IQELGDAFNV MSASVQGKTT ALEEATNFLK SILVSSTEHS IIASDLCGNI
LEFNEGATRM FQYAPEQMIN KSNIKMLYTR EEILSGKFQK ILKSALFTGS YKDEMKLVRK
DGKTFTGYTT ITRRNSFSGS PTGYVIIIRD ITEQKLLEEE VNNYTVHLER IIEERTHKLI
ISEEKYKRLF ESSKDVVFFC DINCQFVDIN QAGIELFGYD TKNDILQLNL IHHLFYKASE
GKIIKETINK NGYVKDFEIA LKRKDGSKIP CMMTGSLRRD MRNNIIGYEG IIIDLTEWKK
IEQEKDILNN INKILASRLD IREVYKSLSE EFHKVIAFDR LSIALLDEKR VEFLTFAVSK
DYRFSELEEG VQYSKQGTLA GKVVEDGEFF VVHDTSRGPF STDPILSKEG IKSRLSVPLI
CKGEIIGSLN FGSKKVNNFT EAHVDVINKI VPQLAIAIDN TRLFDRIKYS EEKYRNLVED
IEDIIFRLDK NGRFMFLNNA LKNVTGYLPQ EFYDAPSLAF KIIHKDDVAL VKHITKEIIG
GRTKVFKGLE YRVYCKNGKE LWFSQNTYPI KNKNGCVIGV EGIIQDITEK KKIEEQIRRS
ERLASIGELA ASIAHEIRNP LGAISNSVCM LKRDLVLSDD DKNLFNMVVE ETEWLNNIIS
NFLTFAHPAE YHFTKSDIAK MVEETLILLK KDARFNGNIR IKKNYSKALP KIFLDRIWIK
KVFWNLLINS IDAMPNGGEI SISLKKTGVP NDDKIEIIIS DSGIGIPPER IKKIFEPFFT
TKKSRGTGLG LSIVHRILDN HDGTIDVKSI QNRGTIFTIR LPLNNKKSRT VSV
//
