ID A0A2C9CSM9_9RHOB Unreviewed; 313 AA.
AC A0A2C9CSM9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Lactate dehydrogenase {ECO:0000313|EMBL:SOH94175.1};
GN ORFNames=SAMN06273572_103204 {ECO:0000313|EMBL:SOH94175.1};
OS Monaibacterium marinum.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Monaibacterium.
OX NCBI_TaxID=1690039 {ECO:0000313|EMBL:SOH94175.1, ECO:0000313|Proteomes:UP000220034};
RN [1] {ECO:0000313|EMBL:SOH94175.1, ECO:0000313|Proteomes:UP000220034}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C7 {ECO:0000313|EMBL:SOH94175.1,
RC ECO:0000313|Proteomes:UP000220034};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
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DR EMBL; OCTN01000003; SOH94175.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2C9CSM9; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000220034; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029753; D-isomer_DH_CS.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003719}.
FT DOMAIN 29..313
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 106..282
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 313 AA; 32937 MW; 80E8BD9232C1AC7C CRC64;
MKIFVTRRLP DSIMARARAL GAELHDSDEV LGDGARAALL HDYDAILCTL GDRFSADMFA
GDLRCKIIAN FGVGYNHIDA DAAKGAGITV TNTPGVLTDA TADLAMTLML MALRRAAEGE
RMVRADAWAG WTPTQMLGQN VTGRTLGIIG MGRIGQAMAR KAHYGFGMEI VFYNRSAKEL
DFPATQLATV ADVASAADIV AIHAPGGAET KHLFDATAIA AMKPTGILIN TARGDVLDEA
ALIDALQAGA IFGAGLDVYE EEPVVPAALR ALDNVVLLPH LGSATLKVRE AMGDMALDNI
EAFIGGHDVP NPV
//
