ID   A0A2C9GPJ3_ANOAR        Unreviewed;       824 AA.
AC   A0A2C9GPJ3;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Oxysterol-binding protein {ECO:0000256|RuleBase:RU003845};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA016655-PA.1, ECO:0000313|Proteomes:UP000075840};
RN   [1] {ECO:0000313|Proteomes:UP000075840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AARA016655-PA.1}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA016655-PA.1};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the OSBP family.
CC       {ECO:0000256|RuleBase:RU003844}.
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DR   EMBL; APCN01004294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APCN01004295; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APCN01004296; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APCN01004297; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9GPJ3; -.
DR   EnsemblMetazoa; AARA016655-RA; AARA016655-PA; AARA016655.
DR   VEuPathDB; VectorBase:AARA016655; -.
DR   VEuPathDB; VectorBase:AARA21_001639; -.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   CDD; cd13290; PH_ORP9; 1.
DR   Gene3D; 1.10.287.2720; -; 1.
DR   Gene3D; 2.40.160.120; -; 1.
DR   Gene3D; 3.30.70.3490; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR037239; OSBP_sf.
DR   InterPro; IPR000648; Oxysterol-bd.
DR   InterPro; IPR018494; Oxysterol-bd_CS.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR10972:SF102; OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9; 1.
DR   Pfam; PF01237; Oxysterol_BP; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS01013; OSBP; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Lipid transport {ECO:0000256|RuleBase:RU003845};
KW   Transport {ECO:0000256|RuleBase:RU003845}.
SQ   SEQUENCE   824 AA;  91335 MW;  E56C7ADE8D8A7D3A CRC64;
     MAMLEGTLSK WTNVMKGWQY RWFVLDENAG LLSYYTVSSS CMTPVSKEKM MKGVRRGCVR
     LKGAIIGIDD QDVNTFTITV DHKTFHFQAR DAEEREKWVR RLEDSILRHA NRSRALWDQQ
     YNYGSGSTSA QSSAMGFTTG GVGGGPGSGV GAGGGTGSVG GGSSSTPGTS IRRSNNLVLF
     DRKVTEADAF LQLMIDQTTK LEARLETLGD TEEATQLKTI NEHVNAMLDN IKHSIVLLQI
     AKNTANPING IYQGPISSKS ETETEPSESG LVVGVMSTSL PTDIEVADEC RESSRRANIA
     SISVPETSYS SSEGEDDFFD ANDSPFTSSQ LNTPTSNTRT LSEHTGRLSG EEQYASAEDS
     TSNSLKKQDT ISAGQSGLVA PLLVGAGADG VATRTTLHET GLPVAVSGSG VPRRSYDSKA
     LPIRTDGSLD YDALYEDESD NDLSMESHGS VVTHLLSQVK IGMDLTKVVL PTFILERRSL
     LEMYADYFAH PDLFLRIADL KEPRERMIQV VRWYLSAYHA GRKSSVAKKP YNPILGEIFQ
     CHWDIPELPT GDEATNVEVK DGPVPWCRRD QLTFIAEQVS HHPPISAFYA EHYNKKISFS
     AHVWTKSKFL GLSIGVHNIG QGTVTLCDLN EEYIVTFPNG YGRSILTIPW IELGGTVTIT
     CPQTGYRADI DFITKPFYGG KKNRIQGEIY GPNDKKSFIS ISGEWSGLME YKYNDGSKPS
     KFETFVDVNS IPIFKKKVRP VAEQDENESR KVWREVTAGL KANDIEKATN AKFQVEQKQR
     EEAKERKETF GEWDTKYFKG IGESWIYTTP LLHRLTLEKR DSKR
//