ID   A0A2C9GQ48_ANOAR        Unreviewed;       635 AA.
AC   A0A2C9GQ48;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Calmodulin-binding domain-containing protein {ECO:0000259|SMART:SM01053};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|EnsemblMetazoa:AARA016807-PA.1, ECO:0000313|Proteomes:UP000075840};
RN   [1] {ECO:0000313|Proteomes:UP000075840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:AARA016807-PA.1}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|EnsemblMetazoa:AARA016807-PA.1};
RG   EnsemblMetazoa;
RL   Submitted (AUG-2022) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; APCN01005905; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; APCN01005906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2C9GQ48; -.
DR   EnsemblMetazoa; AARA016807-RA; AARA016807-PA; AARA016807.
DR   VEuPathDB; VectorBase:AARA016807; -.
DR   VEuPathDB; VectorBase:AARA21_005759; -.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 2.
DR   InterPro; IPR004178; CaM-bd_dom.
DR   InterPro; IPR036122; CaM-bd_dom_sf.
DR   InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR   PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR   Pfam; PF02888; CaMBD; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   Pfam; PF03530; SK_channel; 1.
DR   PRINTS; PR01451; SKCHANNEL.
DR   SMART; SM01053; CaMBD; 1.
DR   SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          358..434
FT                   /note="Calmodulin-binding"
FT                   /evidence="ECO:0000259|SMART:SM01053"
SQ   SEQUENCE   635 AA;  69790 MW;  0AC4E4BA84386ECC CRC64;
     MKTPCAGNRE TVSAACTEEA GIALVGVHSE YPRYMEERGL GGGVCKGPGT IQGGPGQKHK
     PNVGYRLGRR KALFEKRKRI SDYALVMGMF GIIVMVIENE LSSAGVYNKA SFYSTALKTL
     ISVSTVILLG LIVAYHALEV QLFMIDNCAD DWRIAMTWQR MSQISLELLI CAVHPIPGQY
     YFLWTTKLAN KNKAIGGELV PYDVALSLPM FLRLYLICRV MLLHSKLFTD ASSRSIGALN
     RINFNTRFVL KTLMTICPGT VLLVFMVSLW IIASWTLRQC ERFHDEEHAN LLNAMWLIAI
     TFLSVGFGDI VPNTYCGRGI AVSTGIMGAG CTALLVAVVS RKLELTRAEK HVHNFMMDTQ
     LTKRLKNAAA NVLRETWLIY KHTRLVKRVN PGRVRTHQRK FLLAIYALRK VKMDQRKLMD
     NANTITDMAK TQNTVYEIVS DMSTRQDALE ERITSLEDKL TSLQTQIENL PEVLTRCLTQ
     HQERVDQRRN FLHPDAAATG SSSGLPTPAP PLGSPLMLPH SSFSFRSVPS TSTPAYPWPA
     SPILPPISSR TPHLVPETLL PPSTTSAPTG VGPAASSSSS SVALVPTTAN SSFAHSFGTQ
     SAYGNVAPSY AAHHNNSNAQ SSTGDTHIGS HRTSS
//