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Database: UniProt
Entry: A0A2C9GQH5_ANOAR
LinkDB: A0A2C9GQH5_ANOAR
Original site: A0A2C9GQH5_ANOAR 
ID   A0A2C9GQH5_ANOAR        Unreviewed;       548 AA.
AC   A0A2C9GQH5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   31-JUL-2019, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:AARA016923-PA};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA016923-PA};
RN   [1] {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA016923-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840,
RC   ECO:0000313|VectorBase:AARA016923-PA};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:AARA016923-PA}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|VectorBase:AARA016923-PA};
RG   VectorBase;
RL   Submitted (OCT-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; APCN01000829; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   VectorBase; AARA016923-RA; AARA016923-PA; AARA016923.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000075840};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075840};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    124    147       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    167    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    207    230       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       90    235       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      242    413       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION        1     35       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      505    529       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS      1     22       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   548 AA;  62598 MW;  73BE89AF8D049F93 CRC64;
     MNYDSDQQQQ QQQQQQSLSL APDGTGRWDR SMLKLGPFDP PHSPGGYGEQ FGYSSPITPV
     TPNTPLVCYP MKNRVLRPGV NRKYRKRAIL KNGDCNVVLS RPPRQHLRFL QDIFTTLVDA
     QWRWTLLVFA FSFVGSWLFF AVIWWLISYT HGDLEELHLP DNQSEIGWIP CVYNIYSFTS
     AFLFSIETQH TIGYGVRTTT EECPEAIFVM CFQSIYGLMI QAFMVGIVFA KMTRPKQRSQ
     TLLFSKNAVV CQRDGELCLM FRVGDMRKSH IIGASVRAQL IRTKTTREGE TMAQYQHELD
     VGSDGSSSEL FFIWPQIVVH RIDKNSALYN MSASDMLRER FEVVVILEGT VESTGQSTQA
     RSSYVNTEIL WGHRFEPVVC YNREQQGYEI NYSKFDSTLQ VDTPLCSARE LAEFYRAQDD
     YRPPTDVGDN MSTKTQLERR WKDHYSTIVN TLSQYHLADE AGVGGGTDHL YPTRYLTIQG
     VPRRRKSYVA LQNNLWNLFD RPPNPRLKIT PKEDGAGSPR RVSDDDPIVN SVTVQNINER
     FTAGGGGA
//
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