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Database: UniProt
Entry: A0A2C9GQH9_ANOAR
LinkDB: A0A2C9GQH9_ANOAR
Original site: A0A2C9GQH9_ANOAR 
ID   A0A2C9GQH9_ANOAR        Unreviewed;       441 AA.
AC   A0A2C9GQH9;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   31-JUL-2019, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:AARA016926-PA};
OS   Anopheles arabiensis (Mosquito).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Nematocera; Culicoidea;
OC   Culicidae; Anophelinae; Anopheles.
OX   NCBI_TaxID=7173 {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA016926-PA};
RN   [1] {ECO:0000313|Proteomes:UP000075840, ECO:0000313|VectorBase:AARA016926-PA}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dongola {ECO:0000313|Proteomes:UP000075840,
RC   ECO:0000313|VectorBase:AARA016926-PA};
RG   The Broad Institute Genomics Platform;
RA   Neafsey D.E., Howell P., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Anopheles arabiensis DONG5_A.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:AARA016926-PA}
RP   IDENTIFICATION.
RC   STRAIN=Dongola {ECO:0000313|VectorBase:AARA016926-PA};
RG   VectorBase;
RL   Submitted (OCT-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; APCN01000829; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   VectorBase; AARA016926-RA; AARA016926-PA; AARA016926.
DR   Proteomes; UP000075840; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000075840};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075840};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     57     80       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    134    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       23    162       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      169    342       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      346    370       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      391    441       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    348    370       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   441 AA;  50002 MW;  DDF1868B8E445FFD CRC64;
     MDSLLMYRQT RYSSRRIRKR VIFKQGDCNV IQGNVAKRRR RYLQDIFTTL VDIQWRWTLF
     VFACSFILSW LGFAAIWYLI ALSHGDIQAV GDESHKPCVT YIYGFTSAFL FSLETQHTIG
     YGNRYITEEC PEGIFILALQ SITGVFIQAF MVGIVFAKLS RPKKRAQTLL FSKNAVICHR
     DGMPCLLFRV GDMRKSHIIE AHVTAQIIRR KVTKEGEVLP FYQQNMEVSC DGGDDRLMFI
     WPTIVVHKID RDSPLYGLSA QDMLKERFEI VVMLEGVVES TGMTTQARSS YLPSEILWGH
     RFESVVTFKR ETGEYEVDYT TFNNTYEVDT PLCSARQLRE VKKELNKQNG VTEASSDTDE
     SDTSSVEVSS RKNSLSNGYL RFTPVYANTN EQTNGAAGDT MALPPAIITS GGGAPTVSPG
     SERKKNFRKL SIKEPSMDSL C
//
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