ID A0A2C9JEY1_BIOGL Unreviewed; 447 AA.
AC A0A2C9JEY1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=threonine ammonia-lyase {ECO:0000256|ARBA:ARBA00012096};
DE EC=4.3.1.19 {ECO:0000256|ARBA:ARBA00012096};
DE AltName: Full=L-serine deaminase {ECO:0000256|ARBA:ARBA00041766};
DE AltName: Full=L-threonine dehydratase {ECO:0000256|ARBA:ARBA00042605};
GN Name=106055496 {ECO:0000313|EnsemblMetazoa:BGLB001594-PB};
GN Synonyms=LOC106055496 {ECO:0000313|RefSeq:XP_013067233.1,
GN ECO:0000313|RefSeq:XP_055884462.1};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB001594-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB001594-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB001594-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_013067233.1, ECO:0000313|RefSeq:XP_055884462.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR RefSeq; XP_013067233.1; XM_013211779.2.
DR RefSeq; XP_055884462.1; XM_056028487.1.
DR AlphaFoldDB; A0A2C9JEY1; -.
DR STRING; 6526.A0A2C9JEY1; -.
DR EnsemblMetazoa; BGLB001594-RB; BGLB001594-PB; BGLB001594.
DR GeneID; 106055496; -.
DR KEGG; bgt:106055496; -.
DR VEuPathDB; VectorBase:BGLB001594; -.
DR OrthoDB; 5476420at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR Proteomes; UP001165740; Chromosome 5.
DR GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0006567; P:threonine catabolic process; IEA:InterPro.
DR CDD; cd04886; ACT_ThrD-II-like; 1.
DR CDD; cd01562; Thr-dehyd; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR044561; ACT_ThrD-II-like.
DR InterPro; IPR005789; Thr_deHydtase_catblc.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01127; ilvA_1Cterm; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF01842; ACT; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP001165740}.
FT DOMAIN 58..346
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
FT DOMAIN 373..429
FT /note="ACT"
FT /evidence="ECO:0000259|Pfam:PF01842"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 48359 MW; A0D85ACE547C639A CRC64;
MNGHVENSFD ETNDTSDIDE HSNYVEYTDE VVLDPFCNPE QPVLVNFNDV SAASFKIKGG
IEKTPCNFSQ MSKQYGMNIY FKKDFLQYTG SFKERGARYT LLQLNEEQAK KGVVAASAGN
HALALTYHGH LLNIPVTVVM PIVAPMMKVE ACRQYGANVV VFGRDFGETK QYAMLLSKKK
GLHYINGYDH PHIVAGQGTM GLEIIDQVPQ VDACIVPVGG GGLIAGVAVA LKTLKPSIKI
IGVESERSTG FQAAMAAGKP VYSHVGQTLA DGLAVPVVGV NSLATAKKLI DKVVTVKESS
IALAILRLIE QEKAVVEGAG AAGLAAIIQG CLPELKGKNV VVCLCGGNID TTALGRVIER
GLAAEGRLIR FGVTVSDRPG GIAELTKKIA DMGVSIKDIL HERAWLQTDV FSVMVRCVVE
TRDLDHAKEL ERVMRSNYDH VEFWLDQ
//
