ID A0A2C9JGP1_BIOGL Unreviewed; 722 AA.
AC A0A2C9JGP1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Cationic amino acid transporter C-terminal domain-containing protein {ECO:0000259|Pfam:PF13906};
GN Name=106057454 {ECO:0000313|EnsemblMetazoa:BGLB002259-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB002259-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB002259-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB002259-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013070088.1; XM_013214634.1.
DR AlphaFoldDB; A0A2C9JGP1; -.
DR STRING; 6526.A0A2C9JGP1; -.
DR EnsemblMetazoa; BGLB002259-RB; BGLB002259-PB; BGLB002259.
DR KEGG; bgt:106057454; -.
DR VEuPathDB; VectorBase:BGLB002259; -.
DR OrthoDB; 1421713at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 3.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR029485; CAT_C.
DR PANTHER; PTHR43243:SF89; CATIONIC AMINO ACID TRANSPORTER 4; 1.
DR PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR Pfam; PF13520; AA_permease_2; 2.
DR Pfam; PF13906; AA_permease_C; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 61..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..584
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..613
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 620..643
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 624..674
FT /note="Cationic amino acid transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13906"
FT REGION 509..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 701..722
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 722 AA; 79254 MW; CD4D17007DC4C71C CRC64;
MVIRWQDYLT NNHFPLEDGV DKQLSNGKWI KRQLSRITRV KTIPEDLHET SLRRCLNTFD
ITLLGIGHMI GAGIYVLTGT VVREKAGPSA VLSFLFAGTA ALLSALCYAE FGARIPKAGS
AYSYTYVTIG EIWGFLIGWN IILEHMIGAA SVARAWSGAM DAIFNQAIRN GTIEHIGRLS
HDNEWISEYP DMVAMGITLI AFLIIGFGAK ISVNFNSVFT ILNALVLAFI IIIGFTFADP
SLWSSSSGHG GFFPFGFSGT LSGAATCFFA YIGFEGIAIA SEEARDPEKS IPRATVLSLL
TVTTLYLLVT AALTLMIPYY ETNTSGTVDH GGFFPFGFSG TLSGAATCFF AYIGFEGIAI
ASEEARDPEK SIPRATVLSL LTVTTLYLLV TAALTLMIPY YETNTSGTVA LTVFSLSLWV
GFILLQGFQT PIYAVIVFGA LSALMALLFE ITTLVEFMSI GTLFGYTIVA ASIIILRYQP
VSKCQFKLRA EETQTEAAEP VDTSVVNVSE TTPLSKSDPS TPVKTDKSGL LPKSKSHDDF
GRLRQNLREV PILRRFEPGD GVKSAVVLMG LFMVGLMLVV IEGAEYLRTA TWWAVLLVIV
FSLLIVIFYL VIVAHEKNDA FLTFQIPFVP LIPALSMLIN IALMLSLTYL TWLRLVIWIT
VGLLLYFVYG IHYSRENKKI QGYGPMVEYK GDAALPESTM SGMTEEVKEL QPPRKDEGLY
QQ
//
