ID A0A2C9JJF6_BIOGL Unreviewed; 482 AA.
AC A0A2C9JJF6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Torsin-1A C-terminal domain-containing protein {ECO:0000259|Pfam:PF21376};
GN Name=106071235 {ECO:0000313|EnsemblMetazoa:BGLB003397-PC};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB003397-PC, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB003397-PC}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB003397-PC};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family. Torsin subfamily.
CC {ECO:0000256|ARBA:ARBA00006235}.
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DR RefSeq; XP_013086737.1; XM_013231283.1.
DR RefSeq; XP_013086747.1; XM_013231293.1.
DR RefSeq; XP_013086755.1; XM_013231301.1.
DR AlphaFoldDB; A0A2C9JJF6; -.
DR STRING; 6526.A0A2C9JJF6; -.
DR EnsemblMetazoa; BGLB003397-RB; BGLB003397-PB; BGLB003397.
DR EnsemblMetazoa; BGLB003397-RC; BGLB003397-PC; BGLB003397.
DR EnsemblMetazoa; BGLB003397-RD; BGLB003397-PD; BGLB003397.
DR GeneID; 106071235; -.
DR KEGG; bgt:106071235; -.
DR VEuPathDB; VectorBase:BGLB003397; -.
DR OrthoDB; 5087at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049337; TOR1A_C.
DR InterPro; IPR010448; Torsin.
DR PANTHER; PTHR10760; TORSIN; 1.
DR PANTHER; PTHR10760:SF1; TORSIN-4A; 1.
DR Pfam; PF21376; TOR1A_C; 1.
DR Pfam; PF06309; Torsin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 172..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 420..475
FT /note="Torsin-1A C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21376"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 55..89
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..138
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 482 AA; 54908 MW; C11E89661311F808 CRC64;
MEPMDLDSDG DSSLRQNEIS DMEIVSSSPV VDQNVKEISS FEKLECALSS ILSFDKSPTK
SSGPTQSSAM ENSNMECPEH SSYPSTRNLN RGFGISEDDD YISQFSATQN RSDSNDGFRK
RSKITLPNPT KISNQKKERN IAKSKARSLI VKNSDPNVPN SEPIKQSNCL TLFLKCCTFC
IFSFFVVFCI LLVFNYFQRQ CNTGENFSKR VLEMDLDSNV FGQHIAVNII PSKLETYLQK
FHLIANPQLE CKPLVLSFHG WTGVGKNYVS KIISVTLYHS NWNYFIIPYH FPHEAFQSLY
RTQIKTWIVN NVTECNINVV VIDEMDKAYP EIVEGIADSI IALTKPCHKS VPTIFLLLSN
SFAVDINREF LSFMRASHQN SREQFAFQDV HSISEENVDS WFTYLSHKNL IDAFVPFLPL
EKKHVIQCIK RELVSKRFST DSRSIDNILK ELSFSVFGEL ELSNTGCKRV ADKVDLIMLD
DN
//
