ID   A0A2C9JJZ8_BIOGL        Unreviewed;       793 AA.
AC   A0A2C9JJZ8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Calmodulin-binding domain-containing protein {ECO:0000259|SMART:SM01053};
GN   Name=106074407 {ECO:0000313|EnsemblMetazoa:BGLB003593-PB};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB003593-PB, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB003593-PB}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB003593-PB};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   RefSeq; XP_013090634.1; XM_013235180.1.
DR   AlphaFoldDB; A0A2C9JJZ8; -.
DR   STRING; 6526.A0A2C9JJZ8; -.
DR   EnsemblMetazoa; BGLB003593-RB; BGLB003593-PB; BGLB003593.
DR   KEGG; bgt:106074407; -.
DR   VEuPathDB; VectorBase:BGLB003593; -.
DR   OrthoDB; 4200919at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0016286; F:small conductance calcium-activated potassium channel activity; IEA:InterPro.
DR   Gene3D; 1.10.287.70; -; 2.
DR   InterPro; IPR004178; CaM-bd_dom.
DR   InterPro; IPR036122; CaM-bd_dom_sf.
DR   InterPro; IPR015449; K_chnl_Ca-activ_SK.
DR   InterPro; IPR013099; K_chnl_dom.
DR   PANTHER; PTHR10153; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL; 1.
DR   PANTHER; PTHR10153:SF33; SMALL CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL PROTEIN; 1.
DR   Pfam; PF02888; CaMBD; 1.
DR   Pfam; PF07885; Ion_trans_2; 1.
DR   Pfam; PF03530; SK_channel; 1.
DR   PRINTS; PR01451; SKCHANNEL.
DR   SMART; SM01053; CaMBD; 1.
DR   SUPFAM; SSF81327; Small-conductance potassium channel; 1.
DR   SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE   4: Predicted;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        467..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        498..522
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        590..608
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        639..663
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        675..694
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        706..726
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          744..793
FT                   /note="Calmodulin-binding"
FT                   /evidence="ECO:0000259|SMART:SM01053"
FT   REGION          1..81
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          357..377
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..49
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   793 AA;  88214 MW;  32C11186538859FC CRC64;
     MSVLFGEQAG LRQRVDSTEQ LLGEGSGAHS EDRGAPHGTD NKAAELSAEC ERRNPCSSAP
     HSDSPTDGKE PPAAPEASRH RPVYRTCKYS PFISQAGTAE FVHSHYGDNN ANIRTVDLDF
     VGSTVNNNNN RLSVSVDHSD FSLDLHARSE IPAVPYHDMD ARETRIPEVS VPFSPVTYLT
     DLNNLEPLTS DVEQAECLDH SSTVVVSSAQ EGPAGRNIYI NNNTKNKGNG VLEVNDGRVN
     KGYTSPDIEL HSYAFQSEHT PGSASDKFQP PRLKVALSDS DPQQRSPMFQ ATPQQAANTL
     GKWKLRNMGP SYELASTSTE PAPTFNVVSK SELNLRAPNC TRSGGRSPYF YNQRDKARAN
     SEEEGGRAYS DDGGKHNTHT LSDIGADYMR INGAIGSFKQ LQKPTSMQSL PTSSKLSYTE
     EAGFALVSGS DFQKYTDERL QHKVRQKPSV GYRLGKRRAL YQKRKKISDY CLVFGMFGIA
     VMVLETELTM AHVYDKSAFY SIALKSLISI STIILLGLIL AYHALEIQLF AIDNCVEDWR
     IAISWRRALQ LLVEFFICAI HPIPGDVTFT WSGTLAESGK RFDSEVSIDV ILSVPMFLRL
     YLICRVMLLH SKLFTDASSR SIGALNRIHF DTKFVLKTLM TICPGTVLLV FMLSLWIIAG
     WLVRACERHH EDEHANILNS MWMIAITFLS IGYGDIVPNT YCGRGIAISV GVMGSGCTAL
     VVAVIARKLE LSRAEKHVHY FMMDTQLTKR LKNAAANVLR ETWLIYRYTK LVKKVNVSKV
     RSHQRKFLQA IHR
//