ID A0A2C9JKU2_BIOGL Unreviewed; 282 AA.
AC A0A2C9JKU2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Pancreas transcription factor 1 subunit alpha {ECO:0000256|ARBA:ARBA00041035};
DE AltName: Full=Pancreas-specific transcription factor 1a {ECO:0000256|ARBA:ARBA00043211};
GN Name=106058136 {ECO:0000313|EnsemblMetazoa:BGLB003958-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB003958-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB003958-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB003958-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013070971.1; XM_013215517.1.
DR AlphaFoldDB; A0A2C9JKU2; -.
DR STRING; 6526.A0A2C9JKU2; -.
DR EnsemblMetazoa; BGLB003958-RB; BGLB003958-PB; BGLB003958.
DR GeneID; 106058136; -.
DR KEGG; bgt:106058136; -.
DR VEuPathDB; VectorBase:BGLB003958; -.
DR OrthoDB; 5403747at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11417; bHLH_TS_PTF1A; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR23349; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST; 1.
DR PANTHER; PTHR23349:SF59; PANCREAS TRANSCRIPTION FACTOR 1 SUBUNIT ALPHA; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 131..183
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 87..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 282 AA; 32464 MW; F5F6B324BD7B4236 CRC64;
MCQLLSASPQ SSTMNAHGLT FQHLHHEHFH QIQHHHPHNM IQEHPQTQQL PLQYYHELQH
QLQEEQTHPH QLYTSFRLSY GYSPLHSPSS PSSGTILQSP SSDEMPDYPP GYNCLKASRR
RKRKCQQQQV QQRQAANMRE RKRMQSINDA FEGLRSHIPT LPYEKRLSKV DTLRLAIGYI
GFLSEIVQSD VSSKESVHTH VHEQPKKVII YCHAGPNEDF DLYGPPPLTG HSLSWRDLKH
PSLGPRHTMV AKIWTPEDPR SHKLQDADCS GMLHSTVDST DL
//
