ID A0A2C9JRK1_BIOGL Unreviewed; 474 AA.
AC A0A2C9JRK1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Galactokinase {ECO:0008006|Google:ProtNLM};
GN Name=106065030 {ECO:0000313|EnsemblMetazoa:BGLB006915-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB006915-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB006915-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB006915-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the GHMP kinase family. GalK subfamily.
CC {ECO:0000256|ARBA:ARBA00006566}.
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DR RefSeq; XP_013079231.1; XM_013223777.1.
DR AlphaFoldDB; A0A2C9JRK1; -.
DR STRING; 6526.A0A2C9JRK1; -.
DR EnsemblMetazoa; BGLB006915-RB; BGLB006915-PB; BGLB006915.
DR KEGG; bgt:106065030; -.
DR VEuPathDB; VectorBase:BGLB006915; -.
DR OrthoDB; 177392at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004335; F:galactokinase activity; IEA:InterPro.
DR GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR Gene3D; 1.20.1440.340; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.3170; -; 1.
DR InterPro; IPR000705; Galactokinase.
DR InterPro; IPR019741; Galactokinase_CS.
DR InterPro; IPR019539; GalKase_N.
DR InterPro; IPR013750; GHMP_kinase_C_dom.
DR InterPro; IPR036554; GHMP_kinase_C_sf.
DR InterPro; IPR006204; GHMP_kinase_N_dom.
DR InterPro; IPR006203; GHMP_knse_ATP-bd_CS.
DR InterPro; IPR006206; Mevalonate/galactokinase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00131; gal_kin; 1.
DR PANTHER; PTHR10457; MEVALONATE KINASE/GALACTOKINASE; 1.
DR PANTHER; PTHR10457:SF7; N-ACETYLGALACTOSAMINE KINASE; 1.
DR Pfam; PF10509; GalKase_gal_bdg; 1.
DR Pfam; PF08544; GHMP_kinases_C; 1.
DR Pfam; PF00288; GHMP_kinases_N; 1.
DR PIRSF; PIRSF000530; Galactokinase; 1.
DR PRINTS; PR00473; GALCTOKINASE.
DR PRINTS; PR00959; MEVGALKINASE.
DR SUPFAM; SSF55060; GHMP Kinase, C-terminal domain; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00106; GALACTOKINASE; 1.
DR PROSITE; PS00627; GHMP_KINASES_ATP; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 25..74
FT /note="Galactokinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10509"
FT DOMAIN 134..173
FT /note="GHMP kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00288"
FT DOMAIN 372..446
FT /note="GHMP kinase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08544"
SQ SEQUENCE 474 AA; 52246 MW; 8B3D33C71582CBFF CRC64;
MAQDKNPPTL PIPEDKKERF EKIKAKFIEI YGEEPKLFSR APGRVNLIGE HIDYCGYSVL
PMAVELDIVM AVSPDTQGQI SLVNTDPQYQ SYNVDVNQIV ITKDVPHWYK YVLCGIQGII
EHFQSDTLRG FKAVVDGTVP RSAGLSSSSA LVCCSALSML KANEWTMSKE QLAEDCFVRG
REFRLVCQGQ RVQTALSGAE SSDCFLFKWG TNVCLLQAKL IEFNPLLTQD VLLPPNAAFV
VGNSLAEMNK AATPQFNTRV VECRLAAQVL ATSQEGVKWR EIRRLGELQE KLGYTLDEML
NLVTSKLHPE PYTKQEVCEI LEVTPEELVE TSLSANTTHV ESFSLYNRAT HVYSEAKRVV
QFKAICDQQP GNALEQLGEL MNQSHASCRD MYDCSHPDLD TLVEVSKANG AVGSRMTGAG
WGGCTVSIVN AEKVSSLLAG VKASYYQPNP DKFSKVDEAL FATTPGGGAA FYIA
//
