ID   A0A2C9JRY7_BIOGL        Unreviewed;       411 AA.
AC   A0A2C9JRY7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN   Name=106065598 {ECO:0000313|EnsemblMetazoa:BGLB007090-PD};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB007090-PD, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB007090-PD}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB007090-PD};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR   RefSeq; XP_013079893.1; XM_013224439.1.
DR   AlphaFoldDB; A0A2C9JRY7; -.
DR   EnsemblMetazoa; BGLB007090-RD; BGLB007090-PD; BGLB007090.
DR   VEuPathDB; VectorBase:BGLB007090; -.
DR   OrthoDB; 5474043at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR025483; Lipase_euk.
DR   PANTHER; PTHR11005:SF100; LIPASE-RELATED; 1.
DR   PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963,
KW   ECO:0000256|PIRNR:PIRNR000862};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          95..394
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   ACT_SITE        189
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT   ACT_SITE        360
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT   ACT_SITE        388
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ   SEQUENCE   411 AA;  46151 MW;  628E03F7C35AC22E CRC64;
     MCHRLEVSLT ELGETNMSSV WFTFAAVIFC AASESSTKFS QVSLDPEVSM TPTELITSKG
     FPCENYYITT EDGYILNTLR IPHGRHNGHL KGPKPVVVLQ HGLLGSCTHF LTNLVNESLA
     YLLADAGADV WIGNSRGNIY STNHTHLDPK GKEFWQFSWD EMAKYDLPAM INFVLNTSGV
     DQIFYVGHSQ GTTIAFAEFG ENPELASHIK HLIAMAPVAQ VWNTESPIRK LAPLAKEIEI
     FFKVLGTGDL NISPTIMKLL AGTLCDRWSV LCENVLFVLG GYDYSSLNKS RVPVYIAHNP
     GGTSVRDILH WAQAINSKNF QHYDYGSAQE NMIHYGQPTP PLYDPKKVKV PVAIFRGDQD
     WLADPTDVKW LLPQLLVTHD IDIPHYEHLD FIWAFDAPTY IYKEIIKIVF S
//