ID A0A2C9JVC4_BIOGL Unreviewed; 502 AA.
AC A0A2C9JVC4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Wntless-like transmembrane domain-containing protein {ECO:0000259|Pfam:PF06664};
GN Name=106069622 {ECO:0000313|EnsemblMetazoa:BGLB008591-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB008591-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB008591-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB008591-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013084781.1; XM_013229327.1.
DR AlphaFoldDB; A0A2C9JVC4; -.
DR STRING; 6526.A0A2C9JVC4; -.
DR EnsemblMetazoa; BGLB008591-RB; BGLB008591-PB; BGLB008591.
DR KEGG; bgt:106069622; -.
DR VEuPathDB; VectorBase:BGLB008591; -.
DR OrthoDB; 5478455at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR InterPro; IPR040416; TMEM181.
DR InterPro; IPR047843; WLS-like_TM.
DR PANTHER; PTHR31918; TRANSMEMBRANE PROTEIN 181; 1.
DR PANTHER; PTHR31918:SF1; TRANSMEMBRANE PROTEIN 181; 1.
DR Pfam; PF06664; MIG-14_Wnt-bd; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..410
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 154..450
FT /note="Wntless-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF06664"
FT REGION 474..502
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 502 AA; 58510 MW; BAD1A6DF7E9619B0 CRC64;
MDNYSFAFAG PGLRNKARSF VSQFSDTFSA FSKFIAPSYY HDRCERSVQM RLYSLNKRQF
VLVFVTFFVC FLISVLVGIA GPHIIDSHTV NGSLIYKEPQ NKQLGSKFEQ EFTMGILIRG
GNGDSQSVEE SSTNPQLSLE LHNRTRKLKC SGTNCDDLIV MHLGYLDFAY YYITVIFYDL
DVNKLSISNV KFTFKSYNPS FTQTEIWIRF VFLVFTFIMT CWYSHSLRKF SIRDWSIEQK
WMSLLLPLLL LYDDPIFPLT FLVNSWLPGM LDGLFQASFL CALLLFWLCI YHSVRQTDRH
FIRFYLPKLI IVGLIWLCAV ILASWQEYNE LQDPTYYYRL DTTNFEGFKI MFFIFGGFYL
LYLLYLLVRA FAELRLMPFF DLRLKFMTAL MIIVVSISIT ITVMRFGGGA LQDNFVSELA
TNYENSAEFV SFYGLLNFYL YTMAFVYSPS PNAMFETHFK DNPTLSMLND SDEEVHYSSD
TEETSLSRNR NSLIDSDDET AR
//
