ID   A0A2C9JVG5_BIOGL        Unreviewed;       355 AA.
AC   A0A2C9JVG5;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN   Name=106069782 {ECO:0000313|EnsemblMetazoa:BGLB008660-PB};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB008660-PB, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB008660-PB}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB008660-PB};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + H2O + N(6)-methyl-AMP = IMP + methylamine;
CC         Xref=Rhea:RHEA:16001, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:58053, ChEBI:CHEBI:59338, ChEBI:CHEBI:144842;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16002;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
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DR   RefSeq; XP_013084978.1; XM_013229524.1.
DR   AlphaFoldDB; A0A2C9JVG5; -.
DR   STRING; 6526.A0A2C9JVG5; -.
DR   EnsemblMetazoa; BGLB008660-RB; BGLB008660-PB; BGLB008660.
DR   KEGG; bgt:106069782; -.
DR   VEuPathDB; VectorBase:BGLB008660; -.
DR   OrthoDB; 20281at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   CDD; cd00443; ADA_AMPD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF42; ADENOSINE DEAMINASE-LIKE PROTEIN; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
FT   DOMAIN          16..344
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   355 AA;  40440 MW;  B442B7E22B221380 CRC64;
     MKMSDLDLQK FCHRLPKVEL HAHLNTTYSL RTLRLLLESN NGSENIEDMY FTTSHPIAES
     FKLFTKIQSL VTTPEDVYIL TKSIIEEYAQ ENVKYLELRS TPKHIPSSGM TKEVYLRTMI
     EAIKDSESEG YPIIVRILVS IDRRQGLENA RVAVDLAEKL MNEDNIVVGI DFSGDPEVGD
     AADYIPVFLD AAKRKLKLAL HLAELNKEHS FQETVKVLEQ CCNLPIRIGH GTFLHHAQQN
     DKWSALANLV YTKKIPIEAC ITSNLKTETV HCLEQHHFKY WKDRGHPVIL CADGKGVYNT
     SLSQEYFLAM SAFQLTQQEL KDYVVGTLDS IFGSDEIKEE LRTEFTTLMS TLPSV
//