ID A0A2C9JVZ3_BIOGL Unreviewed; 474 AA.
AC A0A2C9JVZ3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Protein Tob1-like {ECO:0000313|RefSeq:XP_013085643.1, ECO:0000313|RefSeq:XP_013085644.1};
GN Name=106070319 {ECO:0000313|EnsemblMetazoa:BGLB008901-PD};
GN Synonyms=LOC106070319 {ECO:0000313|RefSeq:XP_013085643.1,
GN ECO:0000313|RefSeq:XP_013085644.1, ECO:0000313|RefSeq:XP_013085646.1,
GN ECO:0000313|RefSeq:XP_013085647.1, ECO:0000313|RefSeq:XP_013085648.1,
GN ECO:0000313|RefSeq:XP_013085649.1, ECO:0000313|RefSeq:XP_013085650.1,
GN ECO:0000313|RefSeq:XP_055878013.1, ECO:0000313|RefSeq:XP_055878014.1};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB008901-PD, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB008901-PI}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB008901-PI};
RX PubMed=15562597; DOI=10.1645/GE-284R;
RA DeJong R.J., Emery A.M., Adema C.M.;
RT "The mitochondrial genome of Biomphalaria glabrata (Gastropoda:
RT Basommatophora), intermediate host of Schistosoma mansoni.";
RL J. Parasitol. 90:991-997(2004).
RN [2] {ECO:0000313|EnsemblMetazoa:BGLB008901-PI}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB008901-PI};
RA Warren W., Wilson R.K., Hillier L.W., Minx P.;
RT "Sequence assembly of the Biomphalaria glabrata genome version 4.3.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblMetazoa:BGLB008901-PD}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB008901-PD};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [4] {ECO:0000313|RefSeq:XP_013085643.1, ECO:0000313|RefSeq:XP_013085644.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BTG family. {ECO:0000256|ARBA:ARBA00007989}.
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DR RefSeq; XP_013085643.1; XM_013230189.2.
DR RefSeq; XP_013085644.1; XM_013230190.2.
DR RefSeq; XP_013085645.1; XM_013230191.1.
DR RefSeq; XP_013085646.1; XM_013230192.2.
DR RefSeq; XP_013085647.1; XM_013230193.2.
DR RefSeq; XP_013085648.1; XM_013230194.2.
DR RefSeq; XP_013085649.1; XM_013230195.2.
DR RefSeq; XP_013085650.1; XM_013230196.2.
DR RefSeq; XP_055878013.1; XM_056022038.1.
DR RefSeq; XP_055878014.1; XM_056022039.1.
DR STRING; 6526.A0A2C9JVZ3; -.
DR EnsemblMetazoa; BGLB008901-RB; BGLB008901-PB; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RC; BGLB008901-PC; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RD; BGLB008901-PD; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RE; BGLB008901-PE; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RF; BGLB008901-PF; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RG; BGLB008901-PG; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RH; BGLB008901-PH; BGLB008901.
DR EnsemblMetazoa; BGLB008901-RI; BGLB008901-PI; BGLB008901.
DR GeneID; 106070319; -.
DR KEGG; bgt:106070319; -.
DR VEuPathDB; VectorBase:BGLB008901; -.
DR OrthoDB; 11568at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR Proteomes; UP001165740; Chromosome 2.
DR Gene3D; 3.90.640.90; Anti-proliferative protein, N-terminal domain; 1.
DR InterPro; IPR002087; Anti_prolifrtn.
DR InterPro; IPR036054; BTG-like_sf.
DR InterPro; IPR015676; Tob1/2.
DR PANTHER; PTHR17537; TRANSDUCER OF ERBB2 TOB; 1.
DR PANTHER; PTHR17537:SF5; TRANSDUCER OF ERBB2, ISOFORM A; 1.
DR Pfam; PF07742; BTG; 1.
DR PRINTS; PR00310; ANTIPRLFBTG1.
DR SMART; SM00099; btg1; 1.
DR SUPFAM; SSF160696; BTG domain-like; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP001165740}.
FT DOMAIN 1..107
FT /note="Anti-proliferative protein"
FT /evidence="ECO:0000259|SMART:SM00099"
FT REGION 185..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 52233 MW; B4D76E5E1AA67F93 CRC64;
MHVEISVALN FVISYLYNKL PRRRVDLFGE ELEVGLKEKF QGHWYPEQPS KGSGFRCLKG
NGDEVDPVLV YAAVKAGLDI TEVRSYLPED LTLWIDPSEV SYKIGEKGPV KVLYSDRKDE
ESNENVDREV QAASRTFNPE AQTFTPESHQ AFTPDLLAFT PDVAAFCSDS TQSFQPIDSL
SSSLSNLSLS PSSPVPPGTW STATSPSSNL FSSAMASPNI VPPSLVGPRA GNLHRQHMTA
AMFAQTKFGS TKLKTQVKRP NRLSPTEFGN YFKQQQRSYA GPQRPRSLSP RDPRVEFLLD
QQQRMLQQQQ QQMSPSLPYG PQFHLQQQQL SPTSLYPEMY RSSALSSAHS SPHLSPHLSP
AGNGPTFKDL IQSNPNLSTI PSSPLNPISR PSSLNPISRP SSLNPISRPS SLTNLRRPTG
FPSLNSPLSN SSSHTGSLGK MNMFSPEGHK SFTDGFNVAS VNYSNNVQHL LMAN
//
