ID A0A2C9K3I7_BIOGL Unreviewed; 214 AA.
AC A0A2C9K3I7;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Transmembrane emp24 domain-containing protein eca-like isoform X1 {ECO:0000313|RefSeq:XP_013096604.1};
GN Name=106079898 {ECO:0000313|EnsemblMetazoa:BGLB012522-PC};
GN Synonyms=LOC106079898 {ECO:0000313|RefSeq:XP_013096604.1};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB012522-PC, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB012522-PC}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB012522-PC};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
RN [2] {ECO:0000313|RefSeq:XP_013096604.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003827}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003827}.
CC -!- SIMILARITY: Belongs to the EMP24/GP25L family.
CC {ECO:0000256|ARBA:ARBA00007104, ECO:0000256|RuleBase:RU003827}.
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DR RefSeq; XP_013096604.1; XM_013241150.2.
DR AlphaFoldDB; A0A2C9K3I7; -.
DR STRING; 6526.A0A2C9K3I7; -.
DR EnsemblMetazoa; BGLB012522-RC; BGLB012522-PC; BGLB012522.
DR GeneID; 106079898; -.
DR KEGG; bgt:106079898; -.
DR VEuPathDB; VectorBase:BGLB012522; -.
DR OrthoDB; 886406at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR Proteomes; UP001165740; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR015720; Emp24-like.
DR InterPro; IPR009038; GOLD_dom.
DR PANTHER; PTHR22811; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22811:SF159; TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 4; 1.
DR Pfam; PF01105; EMP24_GP25L; 1.
DR SMART; SM01190; EMP24_GP25L; 1.
DR PROSITE; PS50866; GOLD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP001165740};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003827};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..214
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041163220"
FT TRANSMEM 182..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..124
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT COILED 133..160
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 214 AA; 24923 MW; 945912B14AD1204C CRC64;
MALTTALVVF CLFLYTNALY FHIGETERKC FIEEIPDETM VVGHYKVQAY DHNAKDYMPV
SPDIGMHVEV SDPESKVVLS RTYAAEGRFT FTSHSAGEHI ICLNSNSSAW FNAGQLRVHL
DINVGEHAVD YQQVQAKDKL TELQLRVRQL LDQVEQITKE QNYQRYREER FRQTSESTNQ
RVLWWSIAQT LILLITGFWQ MQHLKSFFEA KKLV
//
