ID A0A2C9K5T4_BIOGL Unreviewed; 521 AA.
AC A0A2C9K5T4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN Name=106052414 {ECO:0000313|EnsemblMetazoa:BGLB013660-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB013660-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB013660-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB013660-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the IAP family. {ECO:0000256|ARBA:ARBA00006672}.
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DR RefSeq; XP_013063240.1; XM_013207786.1.
DR AlphaFoldDB; A0A2C9K5T4; -.
DR STRING; 6526.A0A2C9K5T4; -.
DR EnsemblMetazoa; BGLB013660-RB; BGLB013660-PB; BGLB013660.
DR KEGG; bgt:106052414; -.
DR VEuPathDB; VectorBase:BGLB013660; -.
DR OrthoDB; 5406876at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0043067; P:regulation of programmed cell death; IEA:UniProt.
DR CDD; cd00022; BIR; 2.
DR CDD; cd16713; RING-HC_BIRC2_3_7; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001370; BIR_rpt.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10044:SF139; DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2; 1.
DR PANTHER; PTHR10044; INHIBITOR OF APOPTOSIS; 1.
DR Pfam; PF00653; BIR; 2.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00238; BIR; 2.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57924; Inhibitor of apoptosis (IAP) repeat; 2.
DR PROSITE; PS01282; BIR_REPEAT_1; 1.
DR PROSITE; PS50143; BIR_REPEAT_2; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 474..509
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 140..170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 521 AA; 56860 MW; 3A9E7ED4C45391C9 CRC64;
MQTCMSLLSK NCLDLKKRIE LSRLSTFAAY PVTANKSAIE LAANGFVYIG NGTSDTVQCQ
FCHMKKENWQ IDFDVRNIHI LESPICPLVT GAYCDNAPWS VQAQGAISAP ISTTSNGKIG
FSKENDSHNS RLASFTSVTL DPKNLNPESS RNLTPSPRSH TLSGSATTAL GNDSFEAPRL
LNAASSNSFL AASTSTAYAA NSSSHADQTA NNGIPVTSVS TSPSNSHSSV SASLFSTDTS
IRSEPSNPQT PNSGHGPTYS ELGIVTDRPK RPEYALKSKR LETFSSWPRD HHLTAHELSE
AGFYYAGYGD CTRCYFCGGG LRNWEDEDDI WVEHTRWFPK CAFLKQKMGN SFVDLVQDLN
KEFEKITMAM ITDKLPSIVS PGSNRDTLKR DPAVTAVTAL GYPQNDVLEV ALSLKEATIP
LSADVILDKL SSDIKQPINS IDESLRTDST ASTLLEKLLH LKEKNNELRQ QIVCKICLDQ
EVTVIFLPCG HLVSCTECAT AMKDCPVCRM NIKGTVRAFI S
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