ID   A0A2C9K637_BIOGL        Unreviewed;       271 AA.
AC   A0A2C9K637;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
GN   Name=106052751 {ECO:0000313|EnsemblMetazoa:BGLB013833-PB};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB013833-PB, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB013833-PB}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB013833-PB};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR   RefSeq; XP_013063639.1; XM_013208185.1.
DR   AlphaFoldDB; A0A2C9K637; -.
DR   STRING; 6526.A0A2C9K637; -.
DR   EnsemblMetazoa; BGLB013833-RB; BGLB013833-PB; BGLB013833.
DR   KEGG; bgt:106052751; -.
DR   VEuPathDB; VectorBase:BGLB013833; -.
DR   OrthoDB; 5385885at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR030456; TF_fork_head_CS_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11829:SF343; FORK HEAD DOMAIN TRANSCRIPTION FACTOR SLP1-RELATED; 1.
DR   PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00658; FORK_HEAD_2; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
FT   DOMAIN          1..53
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        1..53
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          56..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          170..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..80
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..128
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        170..211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   271 AA;  30073 MW;  2E482FF74DE4321F CRC64;
     QGWQNSIRHN LSLNHCFIKV PRDKGTPGKG NYWTMDPNCD ELFEEGNYRR RKRRVKIQNR
     AITGSSGGNA SGCGSVESSD TREGGESDTE NSGHAVPMQR LDSDDHLVDK SHDDHLATKG
     HDDHRSPYDS SSLLWMRQES RACFVKNEDA PDRYSRDYSE DSMCFGKKTS SGASSSFSWS
     PSEADLFPSS KKSHDPQANR ATHNSQPLQR AVDLSRGKGD GSSSTGVVAM EDKTYDSRAT
     ARHSNPQPDA LTPRETVHPR IKEEVIAGEV F
//