ID A0A2C9K777_BIOGL Unreviewed; 536 AA.
AC A0A2C9K777;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:BGLB014430-PE};
GN Name=106065024 {ECO:0000313|EnsemblMetazoa:BGLB014430-PE};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB014430-PE, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB014430-PE}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB014430-PE};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004334}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000256|RuleBase:RU004334}.
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DR RefSeq; XP_013079220.1; XM_013223766.1.
DR AlphaFoldDB; A0A2C9K777; -.
DR EnsemblMetazoa; BGLB014430-RE; BGLB014430-PE; BGLB014430.
DR VEuPathDB; VectorBase:BGLB014430; -.
DR OrthoDB; 3060590at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 1.
DR Gene3D; 1.10.565.10; Retinoid X Receptor; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001723; Nuclear_hrmn_rcpt.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR24082; NUCLEAR HORMONE RECEPTOR; 1.
DR PANTHER; PTHR24082:SF283; NUCLEAR HORMONE RECEPTOR HR96; 1.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00398; STRDHORMONER.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR SUPFAM; SSF48508; Nuclear receptor ligand-binding domain; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004334};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU004334};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU004334};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU004334};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU004334};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU004334};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU004334};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|RuleBase:RU004334}.
FT DOMAIN 39..114
FT /note="Nuclear receptor"
FT /evidence="ECO:0000259|PROSITE:PS51030"
FT DOMAIN 303..536
FT /note="NR LBD"
FT /evidence="ECO:0000259|PROSITE:PS51843"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 536 AA; 60693 MW; 4A5C9FCBEBBF2ACB CRC64;
MVMAGDDSDS SVGSSPPSRT ASQSKREQKR RPKPKDGTIL ICGVCGDRAL GYNFDAISCE
SCKAFFRRNA LKAKPFTCSF EGNCKLDAHT RKFCSGCRLK KCFTIGMKKE WILNEDQLVK
RRQRQQSRGH GSSGNPDIQP CSSTSNDLNG DDSSMPPYIH QNGPVSHLMP GSNNSNDFMP
LTPANYFDTA SPPQKRQYSL SFDGSGSPTS TTSPPIPFST QLQRNPLQGS LKPPVETLAK
VPKVEYPPEE VEPFCRQKSL DFQDLVDSTD ELSNCSLIKE EIVDDREDYT IPLNPIINTS
LRELEAVYNE IFEAPYMPEH LPKLMEKPKT ANQLFNMTDI FIRRLIRFAK HIPEFKSLKQ
EDQIHLLKGG IMEIFYLRSA ISFDSKNSGW KFRLQQMSAP TEAPASQEAK VDSTIIKNVS
APMFMHHMVF VHELQEISKK DRIVLMLLFI IELMSPSRAN LVDTRMVSLS QERHSMWLKA
YLESLYPVSE AKVTYNKLLV KLQDVRNLGK ESCEMAQQLD ITNLEPLLVE VFDLNR
//
