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Database: UniProt
Entry: A0A2C9KB84_BIOGL
LinkDB: A0A2C9KB84_BIOGL
Original site: A0A2C9KB84_BIOGL 
ID   A0A2C9KB84_BIOGL        Unreviewed;       472 AA.
AC   A0A2C9KB84;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   31-JUL-2019, entry version 12.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:BGLB017136-PA};
GN   Name=106052768 {ECO:0000313|VectorBase:BGLB017136-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|Proteomes:UP000076420, ECO:0000313|VectorBase:BGLB017136-PA};
RN   [1] {ECO:0000313|Proteomes:UP000076420, ECO:0000313|VectorBase:BGLB017136-PA}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BB02 {ECO:0000313|Proteomes:UP000076420,
RC   ECO:0000313|VectorBase:BGLB017136-PA};
RX   PubMed=15562597; DOI=10.1645/GE-284R;
RA   DeJong R.J., Emery A.M., Adema C.M.;
RT   "The mitochondrial genome of Biomphalaria glabrata (Gastropoda:
RT   Basommatophora), intermediate host of Schistosoma mansoni.";
RL   J. Parasitol. 90:991-997(2004).
RN   [2] {ECO:0000313|Proteomes:UP000076420, ECO:0000313|VectorBase:BGLB017136-PA}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BB02 {ECO:0000313|Proteomes:UP000076420,
RC   ECO:0000313|VectorBase:BGLB017136-PA};
RA   Warren W., Wilson R.K., Hillier L.W., Minx P.;
RT   "Sequence assembly of the Biomphalaria glabrata genome version 4.3.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:BGLB017136-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|VectorBase:BGLB017136-PA};
RG   VectorBase;
RL   Submitted (OCT-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_013063660.1; XM_013208206.1.
DR   GeneID; 106052768; -.
DR   VectorBase; BGLB017136-RA; BGLB017136-PA; BGLB017136.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000076420; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 2.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000076420};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076420};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434636}.
FT   TRANSMEM     57     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    130    153       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    158       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      158    286       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      302    327       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      441    472       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    302    316       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   472 AA;  53192 MW;  73F5760609A666FE CRC64;
     MGLCRKRSER FVERSRRRRL MHSTGHNVIP INIEGKYWKF LSDIYTTLID IQWRWNILIF
     ISGLVVTWFL FACLFYLLCY LHGDMDEQPE SFTPCLQNVT TITAAYLFSI ETMTTIGYGK
     RYQTEECPEM YILVMLQSII GAGLQFALAS LVVSKTRRAK SSGGFVPVRS FRVHFMSESG
     RSEIFFPWPT QIIHVVDSES PLWSLSRDEL LDGQHELIVV IDAVCGATCR PFQARKSYQT
     SEMMWGYRFS NLEMTCSQGD HYLMDLSNFH QTTPVATSIL SAENKTNLQV MCDSRTTKVV
     DTISSSSPNT PESCSDLAEA TGVHSASDKE LPERANSAGD MLHCKRRYSL GEMIRVAHGQ
     RRFGRRRQSI DDAVNFYKHR PSITDTYLGE GNIMHDAPDA ENSLVLTGLV SRSLSLKGKD
     LADVIKRKSH GTALLFKSFE SSSFSGQDED TPGTKSADQS PPPQKPSLDA SL
//
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