ID A0A2C9KBV3_BIOGL Unreviewed; 2487 AA.
AC A0A2C9KBV3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE RecName: Full=Centrosomal protein of 290kDa coiled-coil region domain-containing protein {ECO:0000259|Pfam:PF16574};
GN Name=106076710 {ECO:0000313|EnsemblMetazoa:BGLB017349-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB017349-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB017349-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB017349-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000256|ARBA:ARBA00004120}.
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DR RefSeq; XP_013092974.1; XM_013237520.1.
DR STRING; 6526.A0A2C9KBV3; -.
DR EnsemblMetazoa; BGLB017349-RA; BGLB017349-PA; BGLB017349.
DR KEGG; bgt:106076710; -.
DR VEuPathDB; VectorBase:BGLB017349; -.
DR OrthoDB; 3030377at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.1490; -; 1.
DR InterPro; IPR032321; Cep209_CC5.
DR InterPro; IPR026201; Cep290.
DR PANTHER; PTHR18879; CENTROSOMAL PROTEIN OF 290 KDA; 1.
DR PANTHER; PTHR18879:SF20; CENTROSOMAL PROTEIN OF 290 KDA; 1.
DR Pfam; PF16574; CEP209_CC5; 1.
PE 4: Predicted;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium biogenesis/degradation {ECO:0000256|ARBA:ARBA00022794};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212}.
FT DOMAIN 1289..1416
FT /note="Centrosomal protein of 290kDa coiled-coil region"
FT /evidence="ECO:0000259|Pfam:PF16574"
FT COILED 58..555
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 617..658
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 708..749
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 801..860
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 903..930
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 965..1037
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1080..1172
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1214..1331
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1386..1417
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1467..1494
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1628..1766
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1792..1902
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1993..2084
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2138..2258
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2283..2314
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2353..2380
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2487 AA; 288708 MW; F468955D7D785D41 CRC64;
MAPLNWPTIE AVNAKSLSEE QADELFGTLK DGKVGDDFDT VKLKKLFEVC QAVMVNRNQL
LEDAMTEAEL EAKKAMKKEQ ELKKEIERAK KELEEIKKHG PSEGGSKDTR YLRGQLQDLE
EMNDKLKLEI KDLNRDLNSE KRAAEKYSER INELEKELKE TREDNDQMRQ DISDYKMQMQ
SQRDNIVSRR GEDAEFKEKL AKKNRELAET MEELQNMTDA NDLLQKRCED LQRNLEEAIT
QMDRTSEDYL KLKNVLQQSD AVTDALREEN ELLKNQVQDL SEQVRSKGEA DDAIMVAVNQ
KVDEWQEIMQ EKDIQMVNLQ DEIFKLKSQL IAANMDSDKA SVSALSEVLK DKDKQIAELT
EKVDQYTIEM EKNAALIEDL NNELHKAGSS QGDRMQTKVR EFQNENKLLR ERLQQAEAEN
KKADQDCRVK DKELSELLER MRQYEAGEYG LAEAVNEIKE GKNQVKIRER EIEELTQYIN
KAELKINELL DENEELRYKL GMDPKAPMDL TEFRKNKAIR QEEMKALNFT LQREIEMLEE
ERVADKKKIR KLAQQLGQRA VALGLTAEDM LAVQDYTETL KAKRQVQEEQ QSAAVIIRQQ
VQKEESMIRG KEWDKDYKEN VAELHKLEVQ VAELRAQNQQ LNKDNENLEA GFKEVMQALQ
KGATEGQGDV DSSAPVMQFP AIERMLAAIE AKKVLGNYDT TYFLKEQMDI LKGRNEELRN
TLREIRVEVT KTSLERDKAF EKIEKLEKDH FMFSEAGAGP GMFQFMKLPE GMAPSSSEVI
AHLNEHLIIT LQELSQREGV MKKTEAAFEN YKRKYAVLRH QQGMLYQEYL KEKSVWQEDM
EKYSKQLKEL QGQREEDLVR IQEFDRLVDT LSTDDVEVRR RLSEMTRRIT VLRVNEKALT
RRHAIMEEIE TQLRREVERQ RNEMGQMEAA VSERIGYLQR YKDMAAFKIA ALQKALEDSV
PSADLEKVNK QYHNLTEKYR DMLEKGNTLV SKAEALEGLE GEIKQLTADN EVLKKTLEME
KEKLHALEAA MEELHRRGVA SGSEVSVTDG DIISISKKIT MLEMKELNER QRAEHASHMY
QQQRQILHEM ESRNKELEEK FAEVTKMNLE MQKIERDMRD ELSNSVTKSI SDADRKRISV
LEETELTLKQ EISKLKEMAE IASTQVRTLE TQHIAREKEY QSLRQQLLDF QVQSDEKTII
GKLHRHIVQL QVSEGSAIKR LEEAQKKVTK LEAQMLRQEQ RVDEKDQTIY HTRQEAQGKA
RYLRKSLQEL RIQFAGAVPL SKQEKFSRSM MQLQQDKAKL EKDLKESREH KNEMEDKLAA
LSLQQNSLQE LIAVLKDGRG AQKVAEWHSK IDGIRLDELK QRRMCAKLQQ KVRYLEEIIT
SHEVTISELE ADNVRMMKDY EEKQMRWELR ETELERTIIT MEKHTAEIAG AASKFELAVG
SLPSAKLPVA NQLEQAISTI KGNVKVILDT QAENKSLKAR NQELEKLLRD SERGILERDK
LISELRLRMP ATADRDDIII QAQAKVTQAI KKAETGGIDY ESQQALKIAQ STVHSLQQRI
NQKDETIAKY MILLKQGRED MVQMNQRHEE ELRAMQHKIH MNTDLAFSKF KEAARELINK
QSSSKTVTAQ QLSRLNELED TVAEQENTIS ALHEKIKQKE EEILKLHASL SIFNRNLKSE
QTRLAEQHGE IVGKKESEIE MVSRENEDLR KEVKLLQDEV AALKDVNQRG PTATMKNMVE
RLKNQLALKE KQHQALSKAL TDLRADMVSQ AQVLANDASQ EKNIQKIINE HTKQISDQLE
DQQTLADRLK KELKKKKDEE GALQTELEDV KEELNKKERT IEKLKASKAR LESEVDELEK
KMEKITAARS LKAGEFEKQQ ELDDMRRKCR ALEDQLSRQL AAEKPYEQKE EKTKQEDTIR
WEESKKWQRT IEKMKVKIKE RDKEIETLNG TVNRLKALLE RTNREKEIQA PLIQKTSAVS
LSAAPGGKLD HEREDLKATI YKLQDEIRTL KHQALMSQDA ALAEVQMRNQ HLREQLEQME
RAMAARPSDS GVSAAEYQKL FLKNQELQRD VLRLNEENIE LRFEVESSRK DIPRLKERVQ
DLQSYVEALK FENGQLTGDS ARSSLSSIKR IGESGKSQRE LEKTIALLKK VVERVQAENT
ALKKAPGVVS QEQLNLLKRE NDGLKSQLEE LRQTMGLELS ERYTAQQKGT AKMVNDFDKL
RKELAKEKDE NEKLRMKIRS LEVQAEHQDK ELRSTKTKLE VEAVKKPSMS TLDSQGWKSA
VQTRMYEEKI KGMEADLEKK SKQLQDNKVL LRDAAEREQA LLREKDDFLQ KIAILERFPS
GSGAVDSNLM KDYQQSRVRV DRLENEKKEL LNELRLARQN QSGSDTSQIN DDVLTKASNY
DKIMRENIEV HMQLKSVELD KEKLRREVDK LKKELNNFGP EFFEEIEDLK YNYKQSLQHN
VLLEDKLKQV AQQFGLSIEI PKKISTK
//
