ID A0A2C9KCF4_BIOGL Unreviewed; 316 AA.
AC A0A2C9KCF4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=leucine--tRNA ligase {ECO:0000256|ARBA:ARBA00013164};
DE EC=6.1.1.4 {ECO:0000256|ARBA:ARBA00013164};
GN Name=106079244 {ECO:0000313|EnsemblMetazoa:BGLB017510-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB017510-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB017510-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB017510-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363039}.
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DR RefSeq; XP_013095850.1; XM_013240396.1.
DR AlphaFoldDB; A0A2C9KCF4; -.
DR STRING; 6526.A0A2C9KCF4; -.
DR EnsemblMetazoa; BGLB017510-RA; BGLB017510-PA; BGLB017510.
DR KEGG; bgt:106079244; -.
DR VEuPathDB; VectorBase:BGLB017510; -.
DR OrthoDB; 2876972at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004823; F:leucine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006429; P:leucyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR InterPro; IPR002302; Leu-tRNA-ligase.
DR InterPro; IPR015413; Methionyl/Leucyl_tRNA_Synth.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43740:SF3; LEUCINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43740; LEUCYL-TRNA SYNTHETASE; 1.
DR Pfam; PF09334; tRNA-synt_1g; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363039};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363039};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363039};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363039};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363039}.
FT DOMAIN 85..204
FT /note="Methionyl/Leucyl tRNA synthetase"
FT /evidence="ECO:0000259|Pfam:PF09334"
SQ SEQUENCE 316 AA; 37079 MW; C655C4F38C60B6C7 CRC64;
MTILKKPLTW CKTVYLYQNR PSLLGLWARS IFCETHKWDP QLTLEKKIEI ENYWKPIVKS
LDGQQSKLTD STAHEGREKF YALSMFPYPS GNLHLGHVRV YTISDVMARY HRSLGKFVIH
PMGWDAFGLP AENAAIERGI KPKDWTYSNI DRMKKQLMEF GFSFDWSREF ATCDPDYYKW
TQFLFLKMYD AGLAFQKKVS QIFFFFENNN FSICELNYGL VFYVNNVAIA DIGVAYKDLS
SLTTELALDL VTKDSTFIDQ FSQYTVQKYS FFHDKHKASL KLTIPEYKFP IASETTAQLR
KQEKKLSKQK KRLYSV
//
