ID A0A2C9KSE8_BIOGL Unreviewed; 463 AA.
AC A0A2C9KSE8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=5'-3' exonuclease domain-containing protein {ECO:0000259|SMART:SM00475};
GN Name=106064509 {ECO:0000313|EnsemblMetazoa:BGLB023011-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB023011-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB023011-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB023011-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013078531.1; XM_013223077.1.
DR AlphaFoldDB; A0A2C9KSE8; -.
DR STRING; 6526.A0A2C9KSE8; -.
DR EnsemblMetazoa; BGLB023011-RA; BGLB023011-PA; BGLB023011.
DR VEuPathDB; VectorBase:BGLB023011; -.
DR OrthoDB; 3685870at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd02022; DPCK; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR001977; Depp_CoAkinase.
DR InterPro; IPR040982; DNA_pol3_finger.
DR InterPro; IPR004805; DnaE2/DnaE/PolC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR NCBIfam; TIGR00152; dephospho-CoA kinase; 1.
DR PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR PANTHER; PTHR32294:SF0; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR Pfam; PF01121; CoaE; 1.
DR Pfam; PF17657; DNA_pol3_finger; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
DR PROSITE; PS51219; DPCK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 129..396
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 463 AA; 53644 MW; E34A470B760E7F7A CRC64;
MVEPNKFSDL CDIISLYRPG PQDQVELYAK RKKDNEQIKL DNDVLEKILK PTLGIIIYQE
QIMQIASSFA NLTLAQADNL RRGMSKKDQN LILQQKELFI NGAIKKGYSE TEANRIFDLI
EKFAGYGFNK SHAVAYALLG YYLAYLKANY SEEFYTCLLS NNLGDYKKLS EYMREINSSS
NVKVETFRSM SYENYKAKRK PMPEDLVAQL EPIREYLNLR KFSSYAKEKY EADDVIATIA
TRAIQEDPNI RVKILTSDKD MLQLVNDNIS ILRITSGFKN FDEFNIYNFE KKTKLLPSQI
IDLKIMLGDK SDNYPGRPGS GKTTLLKTIE GRYAAKVHVI YADDIVKNTL YVEHHPCFSQ
LVSNFGEKVI AKENKDNKTI DRKVLLNIIF DNKEQQMKLQ KIVWPFLRRE ISKQLISDKR
PIKLVELGAY LNSDGEFDDL FDEVILIHRN DSSIYDTLRE KNH
//
