ID   A0A2C9KSH4_BIOGL        Unreviewed;       280 AA.
AC   A0A2C9KSH4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN   Name=106056526 {ECO:0000313|EnsemblMetazoa:BGLB023006-PA};
GN   Synonyms=LOC106056526 {ECO:0000313|RefSeq:XP_055882026.1};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB023006-PA, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB023006-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB023006-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
RN   [2] {ECO:0000313|RefSeq:XP_055882026.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC       {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_013068761.1; XM_013213307.1.
DR   RefSeq; XP_055882026.1; XM_056026051.1.
DR   AlphaFoldDB; A0A2C9KSH4; -.
DR   STRING; 6526.A0A2C9KSH4; -.
DR   EnsemblMetazoa; BGLB023006-RA; BGLB023006-PA; BGLB023006.
DR   KEGG; bgt:106056526; -.
DR   VEuPathDB; VectorBase:BGLB023006; -.
DR   OrthoDB; 3234802at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   Proteomes; UP001165740; Chromosome 4.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   InterPro; IPR000301; Tetraspanin_animals.
DR   InterPro; IPR018503; Tetraspanin_CS.
DR   InterPro; IPR008952; Tetraspanin_EC2_sf.
DR   PANTHER; PTHR19282; TETRASPANIN; 1.
DR   PANTHER; PTHR19282:SF158; TETRASPANIN TSPE-RELATED; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
DR   PIRSF; PIRSF002419; Tetraspanin; 1.
DR   PRINTS; PR00259; TMFOUR.
DR   SUPFAM; SSF48652; Tetraspanin; 1.
DR   PROSITE; PS00421; TM4_1; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW   Reference proteome {ECO:0000313|Proteomes:UP001165740};
KW   Transmembrane {ECO:0000256|RuleBase:RU361218};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        54..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        87..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
FT   TRANSMEM        247..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361218"
SQ   SEQUENCE   280 AA;  30744 MW;  5ADA08755344D602 CRC64;
     MGLSGCGKFL KYSMFMFNSV ILVAGCGLLG FGVYVRNSEE KMAQLATILG SFYYTAFSTS
     LIVLGGVVIV ISFLGCCGAI KEVKCMLGTF FVLLFVMLLS MVIGGIIVYV YRENIGDAVL
     TELSKSLNTT YGVSGDREVT KAWDLIQKLF QCCGVSGGVN STTSWAYYRE YTFWFKNQTD
     DMREYVPESC CRNVFGNNRT KCVGGSGYEN IIPAILPPVG AHQENDLLYT NGCYTAIVTF
     LTDNVRILAG VASAVSVLMV LGMTFAICLC RRIKDDFLFD
//