ID A0A2C9L2S4_BIOGL Unreviewed; 418 AA.
AC A0A2C9L2S4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE RecName: Full=Signal transducing adapter molecule 1 {ECO:0008006|Google:ProtNLM};
GN Name=106068640 {ECO:0000313|EnsemblMetazoa:BGLB026308-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB026308-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB026308-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB026308-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the STAM family.
CC {ECO:0000256|ARBA:ARBA00009666}.
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DR RefSeq; XP_013083540.1; XM_013228086.1.
DR AlphaFoldDB; A0A2C9L2S4; -.
DR STRING; 6526.A0A2C9L2S4; -.
DR EnsemblMetazoa; BGLB026308-RA; BGLB026308-PA; BGLB026308.
DR KEGG; bgt:106068640; -.
DR VEuPathDB; VectorBase:BGLB026308; -.
DR OrthoDB; 620063at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd11820; SH3_STAM; 1.
DR CDD; cd03568; VHS_STAM; 1.
DR Gene3D; 1.20.5.1940; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45929; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR PANTHER; PTHR45929:SF3; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF02809; UIM; 1.
DR Pfam; PF00790; VHS; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50330; UIM; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 17..147
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 210..269
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
SQ SEQUENCE 418 AA; 46166 MW; 7A4491A6922B5FEF CRC64;
MPLFANATPF DADVEKATHE MNTTEDWSLL LDICEKVQRQ PNGARDCLKS IVKRLNHKVP
FVSMQALTLL DACVNNCGRP FHLEICSRDF VSECRTLISQ KAHPKVAQKL KLLIKSWAEM
AEFKDDPALN LIPSFYDSLK KEGVDFSDTD IKKSAPDPST VRKEEDDIAK AIALSLQEEQ
QKSLNRGGAS GGSSGLYPTY ATPVSKAVQK EIRKVRALYD FEAAEDNELT FKAGELICVL
DDSDPNWWKG SNHRGEGLFP ANFVTADLTV EPEPEIKVEK KSVQFSDQVE VKTLSLPPGE
EEIDEAKIDE VLALIQNADP TGETQPDSQH PPLQYKIIHT SVTRVYEYSQ EGHPGTVPMT
NYSSLPSVGA VPSLAAVNGS HNPIPQQQPQ FIGGQGYTQA PPPNMSVYHT LPSQQPLL
//
