ID   A0A2C9L419_BIOGL        Unreviewed;       644 AA.
AC   A0A2C9L419;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00498};
GN   Name=106054541 {ECO:0000313|EnsemblMetazoa:BGLB026718-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB026718-PA, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB026718-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB026718-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC         Evidence={ECO:0000256|ARBA:ARBA00001973};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_013065895.1; XM_013210441.1.
DR   AlphaFoldDB; A0A2C9L419; -.
DR   STRING; 6526.A0A2C9L419; -.
DR   EnsemblMetazoa; BGLB026718-RA; BGLB026718-PA; BGLB026718.
DR   GeneID; 106054541; -.
DR   KEGG; bgt:106054541; -.
DR   VEuPathDB; VectorBase:BGLB026718; -.
DR   OrthoDB; 70287at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR   PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR   Pfam; PF00264; Tyrosinase; 1.
DR   PRINTS; PR00092; TYROSINASE.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   4: Predicted;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..644
FT                   /note="Tyrosinase copper-binding domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012835769"
FT   DOMAIN          294..305
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   644 AA;  73080 MW;  22C657AA37CA18B0 CRC64;
     MCGHLLIYVL VIMINIEYIS SKMWECSMPV ELQECYNRAG KTDVRDFVGS LYNWLCEQHT
     MQDDPDRKPD IDSRAVQYLM DLSRQAADTG STREKRQSSS GPCVRKEYRM LTLEERRRYH
     DAINTLKNDT SVSPNKYDAI ALIHRGVTNL IAHGGPGFMG WHRYFIRMYE LALRLVNPLV
     CLVFWDSSLD YSLSNPVLSS IWTSEYMGTP RGPVVNGPFA LWRTPDGSQL IRNAGLDGDL
     YTPGVINDLV TRSRYEDLFP ASGGTQRYDF ELHHGAVHVY IGGTMNRLDT AAFDPMFFMH
     HCFVDYLFQR VRAFMRSRGR DPTIYPRLIR SLPRHEAGAP TGFGNTTQAD GYSVSLENTA
     IYEAVPSCSA TSPSCGNRSL VCRNNRCVPT TAPIRLRRAV EDFDQALECD KSSRDDLAVQ
     NDYCINKTCD AENWVYIPVN IFTERPPKFV EYDSYPVRRG RVDKSLDIYS PKANNQTKAM
     ITDRMGDPKT YSRCKKDTPT GQVFLYSQGL NYIGRYKESA IVDQRLSVSI SVGFVGVRKP
     TEGLKGLTKA LIRAHDSCGR VCRVTCRNGS TGAFRPCSGV VCISNEKPLM YGNDYDEATT
     NVFGYKSIRE YPRFMTENVF ISFFCDYPKN YPFAKNVTIS SKKV
//