ID A0A2C9L4U4_BIOGL Unreviewed; 133 AA.
AC A0A2C9L4U4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=WW domain binding protein VOPP1 {ECO:0000256|ARBA:ARBA00035708};
DE AltName: Full=Vesicular, overexpressed in cancer, prosurvival protein 1 {ECO:0000256|ARBA:ARBA00035715};
GN Name=106058541 {ECO:0000313|EnsemblMetazoa:BGLB027097-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB027097-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB027097-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB027097-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004190}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004190}. Late endosome membrane
CC {ECO:0000256|ARBA:ARBA00035628}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00035628}. Lysosome membrane
CC {ECO:0000256|ARBA:ARBA00004363}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004363}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the VOPP1/ECOP family.
CC {ECO:0000256|ARBA:ARBA00006655}.
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DR RefSeq; XP_013071452.1; XM_013215998.1.
DR AlphaFoldDB; A0A2C9L4U4; -.
DR EnsemblMetazoa; BGLB027097-RA; BGLB027097-PA; BGLB027097.
DR KEGG; bgt:106058541; -.
DR VEuPathDB; VectorBase:BGLB027097; -.
DR OrthoDB; 2898530at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR026229; VOPP1.
DR PANTHER; PTHR14971; VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1; 1.
DR PANTHER; PTHR14971:SF2; VESICULAR, OVEREXPRESSED IN CANCER, PROSURVIVAL PROTEIN 1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 133 AA; 15168 MW; D65680409EABCD64 CRC64;
MTKTKSVYSY YCDNDKCTEE EYCCGDNMCC PSYKVWDLWY FWCGVLFFMF LLSLCACLWR
NRFLTNGPVI ISSYSYTPLQ EVDSIGSLSR YHPSNQLYTA PLGTPPPYNQ ISAGNVKNCS
PLPTYAQVVG VSH
//
