ID A0A2C9L775_BIOGL Unreviewed; 1058 AA.
AC A0A2C9L775;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
GN Name=106050643 {ECO:0000313|EnsemblMetazoa:BGLB027688-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB027688-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB027688-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB027688-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013061123.1; XM_013205669.1.
DR AlphaFoldDB; A0A2C9L775; -.
DR EnsemblMetazoa; BGLB027688-RA; BGLB027688-PA; BGLB027688.
DR GeneID; 106050643; -.
DR VEuPathDB; VectorBase:BGLB027688; -.
DR OrthoDB; 3682543at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13186; FERM_C_NBL4_NBL5; 1.
DR CDD; cd17108; FERM_F1_EPB41L5_like; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF25; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
FT DOMAIN 36..320
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 360..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..1044
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 367..404
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..616
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..686
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..754
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 856..879
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..917
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 933..949
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 965..979
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1039
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1058 AA; 118316 MW; 380BFBE909A85D0A CRC64;
MAALIRFFSR RRTRRPQQET YDGLGQKPVP KKKNALVCTI MLLDETDITV DINKKATGGT
LIEQVFYHLD VIEKDYFGLQ YTDHYNVNHW LDPTKQVRKQ VKIGPPYTFR FRVKFYSSEP
NNLHEELTRY QFFLQLKQDI YSGRLPCPYE TLVELCALAL QSELGDYDPD VHSAGTVSEF
RFVPNQSEEM EIDIFEKYKD CSGQTPAQAE LNYLHKAKWL ELYGVDMHTV MGKDNNSYSL
GLTPTGILVF EGTTKIGLFF WPKMTKLNFK HKKLMLVAVE DDENGQSQDH SFQFQCTTEK
ACKHLWKCAV EHHAFFRLKG PVKGPTGRQN FFRMGSRFRY SGRTEYQTAT LNRTRRSVKF
ERKPSHRYSR RPTFERKERE EKLKREAEMK KRMEEDRERR AAIAANKPSV ETTFDSLPDS
ARASMNSNST TATARSSVRV PDSPPPRPPK PGTRKAAKSS SASSEVPESI VPSASAIERL
DNLIKSSALE KGSGEPSGSK SPTTECNINL KEESEKAIAK MKNLDESVPV PVKRKDVNTF
QNNQLKFTGG ASTIPPENMK CNILKAKMEE EHHKDDDDDR SPELSFAAEA PRPRKERQSS
KTSNHSLNNG YESKSSLVEN IADRGVKGST SRVIPENGSI DRKSRNAENE TGSIDRKARY
AINDSGSSEK KSKSTNIDEP YIPEKRQSSR KSPAPQPDFS SMDRRAPRQP VASHNKSFDA
SEIARQRNFS QTSDVFLPSV PSKEITTTPG ATLALSPAPS PPRSRKSKAP SPVPDTALPV
KESAPVKSET LQPELEANAQ KSDTKADNSE IIAKASEGKS GSLKKPLNPF LPERPANPPP
LSSAKSSSLR MKAEAVKQKQ AGKETDIGKE KETENETKPQ KKSLNPFLSD DEEEEEEEAP
PVPFRRDNAK LQNLENESDR KSVPPVPAPR VLSSAGATTT SSSTLKPGST EGHPEPHYKT
TSLKKTRPPP PPPSPTPTRE GSPERGSAKA EKPVSKVAIV ETSFTRTEPV TRKTSSTAKT
QVISIDRSRG DSTASLHHNS HTWSDKKVER KVTLMTEL
//
