ID   A0A2C9LDG3_BIOGL        Unreviewed;      1281 AA.
AC   A0A2C9LDG3;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
GN   Name=106080259 {ECO:0000313|EnsemblMetazoa:BGLB029952-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB029952-PA, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB029952-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB029952-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
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DR   RefSeq; XP_013097056.1; XM_013241602.1.
DR   EnsemblMetazoa; BGLB029952-RA; BGLB029952-PA; BGLB029952.
DR   GeneID; 106080259; -.
DR   VEuPathDB; VectorBase:BGLB029952; -.
DR   OrthoDB; 25176at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR042869; ARHGAP11A/B.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR15670; RHO GTPASE ACTIVATING PROTEIN 11A; 1.
DR   PANTHER; PTHR15670:SF4; RHO GTPASE-ACTIVATING PROTEIN 11A; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
FT   DOMAIN          68..258
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          326..349
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          426..462
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1044..1071
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1172..1195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1224..1281
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..349
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1260..1281
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1281 AA;  142449 MW;  B370CFF8B9C1D3CD CRC64;
     MEDFILINCV ERIDHLYSFI YHNIRELGVK LPKVKKLNKL NQSRKSCSLS SQQQQGQDEN
     YKRKIFGEPL NALPKCFLQN YGYVPEFLVQ ACNLIEQHLH CEGLFRKSGS VSRQKELKLA
     VDEGKSLDGA NVFDTAVLIK QFFRELPEPL FVSVYLDAFI RCYQLPPDKD PKKALLQLCL
     LLPLENIAAL RYTMHMLSKV AATCDKNKMT ANNLALVMAP NMMHSNKGTQ KMSSSEEKLL
     HTQTCIVELL IKNWEQIGMV SGSLQHQVSL MAECFGTDDD LDASDDNTLE ESKEVSQKLR
     RKRSSSLTGF VNSIANGLAK LRRSTDGKGV NMSLNSTQRG ELSHASSGNA NQMQEMLTNT
     VTPCVMRKRR ASGETVPFSA SKKKAILGNL PQRSALASTP FTPASTAKKN QDNRLTLNIT
     TPAMGGKTAR KKLSLFTSPG KVKRESSESP PAMRSKSKSK KNIFKRLSGS RQEKVCDESV
     ETLPRSVSSP TLLECSHKPD VCSVNQIDSI AGLSDGSKKK KKNLISEPSP IIVPVCVSAL
     DLQPQNCEIR RSRRDEFEQK RKKLIQSVKE SHNVDMNQSA DSQLDPTLME AVLPPPEGFA
     DETVVNVNPG DDESEEVDVG SDLESEAGFS TISGGTVIDM RERGGYRKQA AHMNSSSSLI
     SSVSRQITSS LNSLSSMDSL ERLSHGKSSE FSDSHSICSD SVNIHGSDKS EEEEVWVRRK
     SASTSEKLNS FSSETALDAQ QEIALPVYSS VSRKKSISAE DLQSTRMKVN VPTRAHSMYL
     SPCKKYNFKP HLEISKQTHN LLARAGFIQP TNCDAKDVPV PVKSPKRSSY REEMMLSLRS
     SFHERHTHNN ISFRSLRALP NSSLTQDGMN RLNVQERTNM DNGQTAVTNT DKLVDHVENS
     PSLNVPDDGH QKDITGLEVD VTGLDDTVVR NELTDMEDEA ILDVTCTQVD ETTTISSSTM
     MDVTDTEKDV TDIEVDITGV EFHAIGTSDV DPMDTDTETG PKVESQACVK ETNLLKIKRA
     EVLVQRHDSV LNIQHAGLVS QSIKQFSDQQ SHNQHDHDLS GPSVSKRGKS PVRIPTIFAK
     NHNRTRHRVN AHMSRERTGN TSFQNFFPEK ESTDGKEEEK NLFSVSQEEV SSEECYARSG
     SEVSPSKEPV ARMQIDLSDS LMETINDICT PRAQRTRPGE PGQELKSPLK ESTNQIQSAL
     VASQKSGNAH ENLKICSAMK TPHKISLPKE LKPLQISSAA RNQRPQIKRL RVQYSPRKVN
     HRSPKLNSPY RSPKTSVPKQ H
//