ID A0A2C9LFJ1_BIOGL Unreviewed; 3322 AA.
AC A0A2C9LFJ1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:BGLB030594-PC};
GN Name=106070898 {ECO:0000313|EnsemblMetazoa:BGLB030594-PC};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB030594-PC, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB030594-PC}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB030594-PC};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR RefSeq; XP_013086340.1; XM_013230886.1.
DR EnsemblMetazoa; BGLB030594-RC; BGLB030594-PC; BGLB030594.
DR VEuPathDB; VectorBase:BGLB030594; -.
DR OrthoDB; 2950739at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 6.
DR Gene3D; 2.60.120.200; -; 12.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR001791; Laminin_G.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR15036:SF89; NEUREXIN 1, ISOFORM F; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR Pfam; PF13385; Laminin_G_3; 5.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00282; LamG; 6.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 12.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 6.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT TRANSMEM 20..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..225
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1570..1749
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1818..1994
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 1997..2033
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2038..2212
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2210..2391
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 2394..2433
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 2442..2624
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REPEAT 3192..3233
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 3234..3275
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 843..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1770..1816
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2803..2826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1777..1791
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 2001..2011
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 2403..2420
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 3322 AA; 372005 MW; 4CF3E2A5437A7371 CRC64;
MTSRRCCGYS CPGLTSPGGL YLSAVLVLVL ICACESIVFL GERETYAKYP KWNACSNASI
QFEFKTTQKD GLLMFTDDRG QYDYLQVAIV DGSVHLWINF VREINQNLTI ALGKDLNDGR
WHNVAVKRNR MESTLEVDNN QFSRVSFGSD FNFGDFLETN NYMYFGGLPL LYNRSVSNAV
LPVSVQNTPF VGEIRNILYF NCSCMPVRPS VIEDRGTSRR PQEACEIRNP CDKNKDKYCV
CISADDGPGC QCIYKQNCLK DLLADYVLPM DSIRGDIIQN PSGLDAKVYG GADLVRGVHE
MALKIDGVSQ WLRVTGAAHK GECFGDLSHC SNGYYVGLWV QFVSQPTRKA VYMSNGGHSP
DGHGIAMYYY DNGLEFVFKT KDGKEWRAEA RDIFPGRWYH VAASWASDKG LFVYVNGEQA
ASSQQSRRVS ASQNGGQFKD FVIGRSNERT GHDQQVPMIV DDFIFKSSFE TPENVKEEGP
AFLYYLPMEK ITRDRLEMTG GSAKIVGQVQ TVPGLIGNAL SFTSRGEYVD LGDASKKCLG
DLDICKHGFY ISFFIKFQRI DGARSYIFSS PHGMDIYRSG SLFVASAQKG SSIWEAQYRD
LISDVWYFVE VSWSMDGGIV LYVNGEEVDR QVLERPIREP RVTSEMKVFL GRSNQGSRTD
QLAHAELDEM NIFYGTRDML GSLGYIPTDR PENYHIDFEN IQGNRVLHDR LSINLYGSPR
QANGKVGRAL KLNGVNDYAD IYVDSDGCFA DLTLCQHGVL YSMWIHPDRL RDNTYFLSSG
NRGITLLYRG GSLNAVAETA TQRWEASTPS LEVNKWNFVE VSYHPVRGLK LFVNNELKAQ
DASPERFSSQ SSSDRSRFYL GRGKTSESGS TLAEATFDEM ELWQADRDYL ASRGYIQRSR
PKNYLITFEE LIGEDRLKHP TLNINLMQRP MLIPGKVNNA LELSGRGQYA DLGRHNDECM
SNLYLCNQGI TIAAWMRFHR FENNMVFLST GENGILMMYK DGYIQFSVAG DNIITVPRFD
TERWYFVEIT WHPKTGLKVY VDNQLRDKSD KTFTPRSSAR GNFYIGYPNS GDIYTSRYAN
GILDIDELEI WYSGREDLLA FGYINREDYN YSNTNNLGYE SFSFDMSEGS RVIHNKYLVT
LYNDAKLASG RMGSAVSLLG QRQYVDLGEH YQRCFGNIDL CSHGFTMSVW LNPRDLREGT
TFISAPTYNI GYQNGRLRAE FQDKTKRWTT SSNRLRSDEW QRLTMAWHPK KGLSMYLNDE
LADEDTRGID APQRDQPLSE HVYIGRPLSS DRLTTNMMAD ELQVWYDDLT QLRATGQYKV
QAVPINIVFD DFRNNYYRLK DREIRAFGDY RIEQGRSTGS KAIYLYGTTS YLDLGNNFTC
GGDLNSCYQG ATIRLGIRPD QLKENTYFLD SFPVKIYYQN DRLYGQLQTP TQIWTVNSRE
IEPGKWQRVE LTWHPKEGLM MYINGRKVDS QRYGSDQQVQ PPTDWKTYFG RSLEGRSPHV
QGSVDSIEFW TAYRDYLPED GYLRLPPYQP PRPPPTTYRP DSSDKTFDII GDISTEQRTP
RPSQQRRVKI IDFNGAAMVK FNFHELPPDY LKRMQKEDFQ FYFYSRGRAD GLLWLHEDTE
RKMYIALKDG YLIFVIDDYT GQPRVINIGQ RDGVRFDDSR WYLFKMHRDG RTITMTVDDK
YPETFMFSRN MQLLSPGYVY LAGTENTYRS TNGNIVRNFN GGMAQVLYQG ERMEGSQPYI
QEVNLITQFG DNFGEGIRIV NQTWYETVTS SPDPVVTRTP RPRPTWPDPG PEITVPTVAT
RTPRPTLRPT TPPLPPLTQV TIKDKTTYFI IQESFIPSSG NSLSFKFQTI KNKALLLYAM
SNIAGKNFFE FEIYDGLLYF VYNFGGTTKR KLISISEVSD GQSHELSIRF QPNQIIINLD
GSSVRIPLEQ NEQLPTTPTK VHVGGYISYD LLPWHTWARS NYQGCLEDFK MNSQTVDFKS
LVQNLPAKQV ESICVAMPQE CSSRPCTNGY CLNQWGGYYC DCRATEFAGL QCGEYALTGV
YNGSTYNIVR FQPSRQYHVN DISFRFKTLS PDGLIFQTRD RSDKSFIRAE LVGGRVRITT
FFDGKTNSFF VGDENLNDLQ WHTIFVQRRG NHLEFWVDDK PHRKEILPAV DFKLNIDELY
VGGGTGDSSF KNYIGYLQNF FIENIDVFHD LNVNYGPLPH SNQLPPLIFN GVTFPNYQSF
LQLPTLSFSP KLNIHFLFKT NDPNGVILFS EGRNNELFAV ELFDGKIHVK IDIPGKPPLR
ISTPENRRFN DGNWHSVSIV GQTVNGQKQL FMTADELQSS NSYSLIDQIV LQGPLYIGGI
SESVSQKANV KTFLSSKTGY RGCLASVYLG TGLPNLLEVA QGQKVNVLNS CQDIVSQCTK
TTCKNGGVCH DHLNNGTTWC DCSRTGYGGP LCEDEPLGYY FRNERKIDLY GMLIHRTALK
SEHEQDEIVF GLMTDEKNAV LVKLISNIFD DFVEIKLVDG YVVATYDTDG KGGAQTTITN
TDVMVSDKQY HIIKLLRTKD KGVLTVDTVS TTNTHASAHG NFNALEKIFI GGVYQGKKIL
DGYHGIIAGL FVNDKLIFNE KLEFQNDVVQ ATHPFIIGKI EQHSTQGWIT SSPPPVITTL
PPALIPVIPP NIGGGGIAGF GPDVVVFPDL SGGSADDLTN LGPIGDPVAA AQISVIPSLP
AVGPRAGAVM GTILGLAALA SSLMWAFYRC KPGWCAGLKP AETPLSISPP RSNIPLLKQQ
AAVGSATGAG GAMSGSGAGA GGGAARAVGV SGGVAGGTMQ SNSSYYQQSS TNVHQRSDSY
DSATLRATGT FTNKGTAIGT PRMGRHQMGS TSASYTESNV AITPASLQSY HFEGGNSTAD
YDVASGVHSG YQGNTLTSGG GGGYSTSTMS SNYNYTVKTI RNVGGQQAAM GYAAGSLSNV
IVTPGAMGEE IRVDCCLMTG DGHSVVTGSS LGPPQVWNMS TGELLRIMHG ETVGSTNLHL
VCNDKLLVGA INTDLEINQY STPKGVHNYQ FQIWDFASGR PLEMAQQETC SALTVMSDND
KVVFGRSDKF GGGTNIVVWD LMGNQAIKEM RYDAPVGNND YISYISLSQN DRYVVAGFNN
TFDNYAEFVI FDMTLTSYNI SDPNILRLNA TPECTAILPH DEAVTGLRNG DLVVWSLRTG
QPIRQLFSNN GKHAHTREVK AVARSQDNKY LVSASADGTL KVFDLETERH MNTLSGHNDE
VWCACISSDN EIVVSGSRDG TIRLWRLKSG QEICAFNAGV DVFYITMSQD KGTIVALGDK
FGARKLIMLQ VVRSKVKRQV LA
//
