ID   A0A2C9LKD2_BIOGL        Unreviewed;      1386 AA.
AC   A0A2C9LKD2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   13-SEP-2023, entry version 28.
DE   RecName: Full=Transcription initiation factor TFIID subunit 2 {ECO:0000256|ARBA:ARBA00017363};
GN   Name=106056616 {ECO:0000313|EnsemblMetazoa:BGLB031942-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB031942-PA, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB031942-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB031942-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF2 family.
CC       {ECO:0000256|ARBA:ARBA00010937}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_013068884.1; XM_013213430.1.
DR   STRING; 6526.A0A2C9LKD2; -.
DR   EnsemblMetazoa; BGLB031942-RA; BGLB031942-PA; BGLB031942.
DR   KEGG; bgt:106056616; -.
DR   VEuPathDB; VectorBase:BGLB031942; -.
DR   OrthoDB; 11119at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd09839; M1_like_TAF2; 1.
DR   Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR   Gene3D; 2.60.40.1730; tricorn interacting facor f3 domain; 1.
DR   InterPro; IPR042097; Aminopeptidase_N-like_N_sf.
DR   InterPro; IPR014782; Peptidase_M1_dom.
DR   InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR   InterPro; IPR037813; TAF2.
DR   PANTHER; PTHR15137; TRANSCRIPTION INITIATION FACTOR TFIID; 1.
DR   PANTHER; PTHR15137:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2; 1.
DR   Pfam; PF01433; Peptidase_M1; 1.
DR   SUPFAM; SSF63737; Leukotriene A4 hydrolase N-terminal domain; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          273..502
FT                   /note="Peptidase M1 membrane alanine aminopeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF01433"
FT   REGION          1000..1048
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1062..1146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1163..1386
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1000..1040
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1066..1086
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1096..1110
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1197..1216
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1237..1264
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1272..1308
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1314..1337
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1338..1362
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1386 AA;  156865 MW;  D72086D6289D97B3 CRC64;
     MKKDSKYEIS RLFKVSHQIL CINSINFENR SLVGYVELTI WPTVPDLTEI RINSKQCIVY
     RVSVDKKWDA EFSYFDPSLN ICQGNAVKRN IDYFHKCQMN AINAVDPDLG CGELIITFPK
     EVLPTISALG SFQICVEFGL KEPQGGVHFV VPDMPGTMAE RSAHMFTYSL ENQSRLWFPC
     MDTFSEPCTW KIEVTVDRDM TAISCGDLVG VEFTEDLLEK TYHYFLSTPV AAPNIALAVG
     PFEILVDPKM HEVTHFCLPK LMPVLKHTTS YIHQAFEFYE ELMSSRYPYS YYKQVFVDEA
     YCEVSTYSTM SILSTNLLHP TNIIDQTMAS RQLMATAVAQ QFFGSFIAME SWSDAWLTKG
     ITGYLSYLFS KRTFGNNEYR NWVFRDLLEV SEYEQQMGNV VLDPTKHGSN HHFHIQSPHT
     LSPRYIEMFC KKARLVMRML EIRIGTELLL QVLNKLLSLA YNASQQPFSF SSWSNMLLST
     SSFLKIIYTV TGKDIEPFIE QWVYQGGCAR FIGSFVFNRK RNVVELEIKQ DLAPGAMKYV
     GSLNVTIQEL DGSFNHQFKI EENKTKFEIT CHSKSRRNKK KKIPLMTGEE VDMDLTAMDA
     DSPVLWLRLD PDMHLLRTVT FEQPDYMWQY QLRYEKCIVA QFEAIDALGK FPTPPSRLAL
     TDTIENEECY YRVRQDACYC LAKWSDNYYR AALVEALSAS LTPAVTNVSL ITGQIVTAAA
     LSPEMKLVVE EVVRSLNIEK LMPCYKFTVT VSCLYTIRTL QKLGHLPIES DVFKDYTQVG
     IFRDVRVAAI TCLVDFIRGD VTGEHLNWIL DFIENEKDPY LKHHTVTCLT QNPPFRRSER
     SALNIEPLVE RLWEMMCHTS HDSRLRCGLA DLYFILYGRQ RPTCLPVPEI VKMGQKDKKS
     KMESLCLQIN ADDLSVSEPA PSSIAIWNPE LSNIFASPVH EPAMVENSAP ATVKVNLDLD
     ITDDFTDRSS VDVTMHSEDQ SNVIEEAVVT ETVELESDLE SEVTPNLSRP SVQIDLSQGL
     SRHDSISRLS EDSLSNSPPP VSKGHPDDVI VSLDNIIKHD PIIPGKLFQP PSPPPTYHPD
     QPVRVELSPP PVTLEEVKSP LSPPPASPDS RSSPGYIIED ESAQEKQARI SGDVTQENME
     DIKPVVEDLT TEMVEEKQLT VITEDQTDAK IELSPATPTQ LVVDFKKEIK EESQPSPPQS
     SSPPQTPQPP PSAPTPQFSF ASVYQQIPPL PIKHSVSLDT ETPSSSLTLK RKLSVPSYQS
     SPEPETKKIP PLIVSTSVSG GTTILSPNSA KPSLKTTLYL NTSAASTSES RDKSHHKSKK
     KKKKNKHKHK HKHKHDRGDK HERGDKHDKH KPRERLLLDL SEIARASRDS PTVRPTTEQE
     EESSSE
//