ID A0A2C9LP47_BIOGL Unreviewed; 469 AA.
AC A0A2C9LP47;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Orn/DAP/Arg decarboxylase 2 N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106073141 {ECO:0000313|EnsemblMetazoa:BGLB033431-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB033431-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB033431-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB033431-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR600183-50};
CC -!- SIMILARITY: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
CC {ECO:0000256|RuleBase:RU003737}.
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DR RefSeq; XP_013089075.1; XM_013233621.1.
DR AlphaFoldDB; A0A2C9LP47; -.
DR STRING; 6526.A0A2C9LP47; -.
DR EnsemblMetazoa; BGLB033431-RA; BGLB033431-PA; BGLB033431.
DR KEGG; bgt:106073141; -.
DR VEuPathDB; VectorBase:BGLB033431; -.
DR OrthoDB; 317547at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0008836; F:diaminopimelate decarboxylase activity; IEA:InterPro.
DR GO; GO:0009089; P:lysine biosynthetic process via diaminopimelate; IEA:InterPro.
DR CDD; cd06828; PLPDE_III_DapDC; 1.
DR Gene3D; 3.20.20.10; Alanine racemase; 1.
DR InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR InterPro; IPR002986; DAP_deCOOHase_LysA.
DR InterPro; IPR022643; De-COase2_C.
DR InterPro; IPR022644; De-COase2_N.
DR InterPro; IPR022653; De-COase2_pyr-phos_BS.
DR InterPro; IPR000183; Orn/DAP/Arg_de-COase.
DR InterPro; IPR029066; PLP-binding_barrel.
DR PANTHER; PTHR43727; DIAMINOPIMELATE DECARBOXYLASE; 1.
DR PANTHER; PTHR43727:SF2; DIAMINOPIMELATE DECARBOXYLASE 1, CHLOROPLASTIC-RELATED; 1.
DR Pfam; PF02784; Orn_Arg_deC_N; 1.
DR Pfam; PF00278; Orn_DAP_Arg_deC; 1.
DR PRINTS; PR01179; ODADCRBXLASE.
DR SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR SUPFAM; SSF51419; PLP-binding barrel; 1.
DR PROSITE; PS00878; ODR_DC_2_1; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR600183-50}.
FT DOMAIN 8..210
FT /note="Orn/DAP/Arg decarboxylase 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02784"
FT DOMAIN 292..419
FT /note="Orn/DAP/Arg decarboxylase 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00278"
FT ACT_SITE 398
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
FT MOD_RES 20
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR600183-50"
SQ SEQUENCE 469 AA; 52391 MW; 6B98343490A933D6 CRC64;
MYLDALKLLD CESQLNYAVK ANPNFSLLRL IRSQGASATL ISGNEIRLAL EAGFEPTFMM
YNGGGKCQWE TQLAIEHNLL INVDSLWDLK QTLDICRNGF PETRTARLLL RINLNIDSSV
HNFVNTGKAD SKFGLSEKES EACLELLEQP GCPAELVGLH SHLGSTIYQS DVFRLSLERL
LEYRSKLVSR GFIKVSLINI GGGLGIDYKL LEFETKAWQS ESEDNKKNIL QLKEFLLNLE
EDQTDGCSRK NILSSLSAYV NESIAFEDLR LATTVFLSTN KHLGSKVEQI CSSLTAPKPV
HATPLDLIQS VSDLLKGKDV KLIIEPGRSI VANSSAVIAR ILGCKQSSEK RFIILDVSMN
EIIRPCLYGA YHHVTILNNS DSSNKMEKKV FNVVGPVCES SDFLAQNRML PDTCEGYAII
HDVGAYCYSM ASNYNVRMRP AEVLVDGHDC ILIRRPDTYE DFMAPYKEI
//
