ID   A0A2C9LTB4_BIOGL        Unreviewed;       380 AA.
AC   A0A2C9LTB4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN   Name=106069429 {ECO:0000313|EnsemblMetazoa:BGLB034751-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB034751-PA, ECO:0000313|Proteomes:UP000076420};
RN   [1] {ECO:0000313|EnsemblMetazoa:BGLB034751-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB034751-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_013084540.1; XM_013229086.1.
DR   AlphaFoldDB; A0A2C9LTB4; -.
DR   STRING; 6526.A0A2C9LTB4; -.
DR   EnsemblMetazoa; BGLB034751-RA; BGLB034751-PA; BGLB034751.
DR   GeneID; 106069429; -.
DR   KEGG; bgt:106069429; -.
DR   VEuPathDB; VectorBase:BGLB034751; -.
DR   OrthoDB; 2963550at2759; -.
DR   Proteomes; UP000076420; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd11405; bHLHzip_MLXIP_like; 1.
DR   Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   PANTHER; PTHR15741; BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR; 1.
DR   PANTHER; PTHR15741:SF37; LD38259P; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          177..229
FT                   /note="BHLH"
FT                   /evidence="ECO:0000259|PROSITE:PS50888"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          118..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..189
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   380 AA;  41998 MW;  331F3468EE7B0A2D CRC64;
     MIAVGADSQN PQHASSVASI PLPPLGDELP SLSCDLGDIS ISSSEIDQFF QSFSEFSLPP
     DASQMQVETE GSHLSTLTSC DLTSFFFEDL QRPRDLNVEN PVQAQFYHNL NPSFVSEDEA
     TMTPTYPGGI TPQNISRANS PTWSESSGSM STSSVPGTPT GTQSQSSKNS NNPLPRHKRP
     SHKRAEIKRR DKIKTCLDDI KDCIPSLRDK GKLSESAILS KAAEYVRHLK DGCTERGNKA
     EELRREIECL STEIHSFQEN LPATGLNDEP LPATSLDDLY LQWREENSQR SAKFCIFASI
     TSKLFDAFKE IIGPVTTLNA LTAKAQEWQT KFLALPVLRK VILGGMLELS RQDIIVMTPD
     KLQLQVDASN ARVKMEDTFS
//