ID A0A2C9LX10_BIOGL Unreviewed; 330 AA.
AC A0A2C9LX10;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Abasic site processing protein HMCES {ECO:0000256|ARBA:ARBA00015888};
DE AltName: Full=Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein {ECO:0000256|ARBA:ARBA00030390};
DE AltName: Full=Peptidase HMCES {ECO:0000256|ARBA:ARBA00030898};
DE AltName: Full=SRAP domain-containing protein 1 {ECO:0000256|ARBA:ARBA00031130};
GN Name=106067112 {ECO:0000313|EnsemblMetazoa:BGLB035962-PB};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB035962-PB, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB035962-PB}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB035962-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SOS response-associated peptidase family.
CC {ECO:0000256|ARBA:ARBA00008136}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_013081698.1; XM_013226244.1.
DR AlphaFoldDB; A0A2C9LX10; -.
DR EnsemblMetazoa; BGLB035962-RB; BGLB035962-PB; BGLB035962.
DR VEuPathDB; VectorBase:BGLB035962; -.
DR OrthoDB; 204678at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:InterPro.
DR GO; GO:0006974; P:DNA damage response; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1680.10; SOS response associated peptidase-like; 1.
DR InterPro; IPR003738; SRAP.
DR InterPro; IPR036590; SRAP-like.
DR PANTHER; PTHR13604:SF0; ABASIC SITE PROCESSING PROTEIN HMCES; 1.
DR PANTHER; PTHR13604; DC12-RELATED; 1.
DR Pfam; PF02586; SRAP; 2.
DR SUPFAM; SSF143081; BB1717-like; 1.
PE 3: Inferred from homology;
KW Covalent protein-DNA linkage {ECO:0000256|ARBA:ARBA00023124};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670}.
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 330 AA; 37360 MW; 04700307DE2D85E1 CRC64;
MTKKCVDAQH DKNGTRKQPH WVDAPGGQKY YPSYNKAPTS FNPVLTSSQH FVKSDIKSER
DRILMPMKWG MTPSWHHGDP YKVPYETNNC RAEGMLDKKT YKVPLKKGYR CVVLADGFFE
WQTTKEGKQA FLFYFPQPET VKFPFSVLDT SKKELKEHQP SETCIKSELK GEGYTDVGEP
KVKQEFKDEN SGDYTVVEKS GPRLLTMAGV FDVWDPHDGS PPLYSYSVIT VSASSDMAWC
HHRMPAILTT DEEIQDWLDF SNVPLDKAVS LIKPQVCLTY HPVSKAVNSS KCQSEDCVKP
IELGKSKSNA SSNLMLNWLK SGSPAKKKKT
//
