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Database: UniProt
Entry: A0A2C9LXD1_BIOGL
LinkDB: A0A2C9LXD1_BIOGL
Original site: A0A2C9LXD1_BIOGL 
ID   A0A2C9LXD1_BIOGL        Unreviewed;       469 AA.
AC   A0A2C9LXD1;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   03-JUL-2019, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:BGLB035961-PA};
GN   Name=106053848 {ECO:0000313|VectorBase:BGLB035961-PA};
OS   Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC   Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC   Planorbidae; Biomphalaria.
OX   NCBI_TaxID=6526 {ECO:0000313|Proteomes:UP000076420, ECO:0000313|VectorBase:BGLB035961-PA};
RN   [1] {ECO:0000313|Proteomes:UP000076420, ECO:0000313|VectorBase:BGLB035961-PA}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BB02 {ECO:0000313|Proteomes:UP000076420,
RC   ECO:0000313|VectorBase:BGLB035961-PA};
RX   PubMed=15562597; DOI=10.1645/GE-284R;
RA   DeJong R.J., Emery A.M., Adema C.M.;
RT   "The mitochondrial genome of Biomphalaria glabrata (Gastropoda:
RT   Basommatophora), intermediate host of Schistosoma mansoni.";
RL   J. Parasitol. 90:991-997(2004).
RN   [2] {ECO:0000313|Proteomes:UP000076420, ECO:0000313|VectorBase:BGLB035961-PA}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=BB02 {ECO:0000313|Proteomes:UP000076420,
RC   ECO:0000313|VectorBase:BGLB035961-PA};
RA   Warren W., Wilson R.K., Hillier L.W., Minx P.;
RT   "Sequence assembly of the Biomphalaria glabrata genome version 4.3.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|VectorBase:BGLB035961-PA}
RP   IDENTIFICATION.
RC   STRAIN=BB02 {ECO:0000313|VectorBase:BGLB035961-PA};
RG   VectorBase;
RL   Submitted (OCT-2017) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_013064941.1; XM_013209487.1.
DR   GeneID; 106053848; -.
DR   VectorBase; BGLB035961-RA; BGLB035961-PA; BGLB035961.
DR   OrthoDB; 868466at2759; -.
DR   Proteomes; UP000076420; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000076420};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076420};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM    105    127       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    213    233       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       71    238       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      245    417       IRK_C. {ECO:0000259|Pfam:PF17655}.
SQ   SEQUENCE   469 AA;  55337 MW;  1771E070A385E75D CRC64;
     MTGGRPCVLN LFEDHERWEE YKYQTFLFPE RLHSELTVDG ASVEDEPGSR TDRVWRELNS
     RRMKPRRTLL RKEGQSNIAY RGIQKKKVKF LKDLYVTLLD LKWRWAMLIL FLGFFLSYFF
     FSILYFLMSY TLTHLKLCKL TFSNIRWTHL KLCKLTFSHI RLTHLKLLGR LNFCIYRLDS
     YWDALLFSIE TQSTIGYGTI YPNADCAGTL PVVYLQITCG FLLETVLLGF IFVKIARPKH
     RRHTLIFSRN ACICLEDQHL NLQIRVGDIR NSHLIDCHVY GALVKRYVCQ EKYVYPLFQH
     EIEFHAHNMK DKVFLIWPMV LSHKITKDSP LYTLTPEDLI YDKFELIVVL EGTIESTGEM
     VQARTSFTSK EILWGHRFTR VEEYDEKTDK WCINFVRFNN VVPSKTPKCN AKDLTENPER
     VHEVYTEEDP VEIDQLTRQK HTLATSVDTL DTDAVYSTAS EDDQRVEDV
//
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