ID A0A2C9LYT5_BIOGL Unreviewed; 912 AA.
AC A0A2C9LYT5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Alpha-2-macroglobulin bait region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106067229 {ECO:0000313|EnsemblMetazoa:BGLB036531-PA};
OS Biomphalaria glabrata (Bloodfluke planorb) (Freshwater snail).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
OC Planorbidae; Biomphalaria.
OX NCBI_TaxID=6526 {ECO:0000313|EnsemblMetazoa:BGLB036531-PA, ECO:0000313|Proteomes:UP000076420};
RN [1] {ECO:0000313|EnsemblMetazoa:BGLB036531-PA}
RP IDENTIFICATION.
RC STRAIN=BB02 {ECO:0000313|EnsemblMetazoa:BGLB036531-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013081831.1; XM_013226377.1.
DR AlphaFoldDB; A0A2C9LYT5; -.
DR STRING; 6526.A0A2C9LYT5; -.
DR EnsemblMetazoa; BGLB036531-RA; BGLB036531-PA; BGLB036531.
DR KEGG; bgt:106067229; -.
DR VEuPathDB; VectorBase:BGLB036531; -.
DR OrthoDB; 2970602at2759; -.
DR Proteomes; UP000076420; Unassembled WGS sequence.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00112; LDLa; 1.
DR Gene3D; 2.20.130.20; -; 1.
DR Gene3D; 2.60.40.1930; -; 2.
DR Gene3D; 2.60.40.2950; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 1.
DR InterPro; IPR011625; A2M_N_BRD.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR InterPro; IPR001599; Macroglobln_a2.
DR InterPro; IPR002890; MG2.
DR PANTHER; PTHR11412:SF179; LD23292P; 1.
DR PANTHER; PTHR11412; MACROGLOBULIN / COMPLEMENT; 1.
DR Pfam; PF00207; A2M; 1.
DR Pfam; PF07703; A2M_BRD; 1.
DR Pfam; PF01835; MG2; 1.
DR SMART; SM01360; A2M; 1.
DR SMART; SM01359; A2M_N_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..912
FT /note="Alpha-2-macroglobulin bait region domain-containing
FT protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012880753"
FT DOMAIN 537..668
FT /note="Alpha-2-macroglobulin bait region"
FT /evidence="ECO:0000259|SMART:SM01359"
FT DOMAIN 814..905
FT /note="Alpha-2-macroglobulin"
FT /evidence="ECO:0000259|SMART:SM01360"
SQ SEQUENCE 912 AA; 104680 MW; 772C764123F03BCA CRC64;
MWHLICSTIL IAMVSAQQPG GGPPREDNCL IDASVGCSYA RAPQYLVITP KKIRPNQVFQ
IFATILKMEY NQEFVHVIVS IIKDNIEYAN TALRFDRPSS RIMQLQMPSN AQEGKYRLRV
EGRLNEQDTG NIWQNETDID FTTKQASLFL QMSRPLYRQG QKVHFRIIPI LPNMMPKYGS
MVIYVDDPTG IPVRRWQSIQ TNAGGIISQS FTLSDQPNFG TWIIRVEAFG HVYRHPFTVE
DFWEPRFDVN VSVPSYVMET PEISVAGVML ANHTSGRPCI GNASITAFFR PREEIWNRTK
GWEKPYWDAQ AGGTPNSGVP MELPQYKPVH TIPVKDYYMY FAYEYRFIDY FQGRIDFEWT
LEQLMTIAKR GGESGSLVDS EFVFFANVSD WYSGLNRTGW AGTIFFDSKI KLKWVGDQIR
TFKPSQVMRV QVAVTKYDGT PVENVGTVTL TDVTTDSSGT AVQSKSNTQV PKNGIADFEY
QLSATTQTLK LTATYADARK PYSGDNKIYL DPRFNLGTTV PITMYATRYY SPSNSYITIL
TSTDRPQVNE YMVFHVKTSN YVPRIYYQIV AQSNIIIGDW LEMTSRQKTF AVALSRDMVP
TARLVVYYIR QPEEIVVDVL NFFVNGTRQN LVTLNINRGK DFSRDTIEFN AYADPGSYVS
FSGMLLDLYS RGLSDGITEN KLIDELMTYD STQNGSYRHL WRVSDTEYEY VFYHGPDYGI
DANTSFDTAG LLVLTDARVS RLYNDKFCTD QKSFPCFVGI ESQCFKPEQR CDGTIDCVND
GADEWGCTFQ ESKEIHNPAM DRVSRVMRFY DNSSWAWQEI FVKPDGRVDF RVDVPKYPLS
WVINGVSVSR ELGLGIMLKP VRYDAARYMY MQVEHPKHII RGEQVGVRVT VFNYWYDDDY
LEVNCTFLFQ IK
//
